CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044467
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Mitogen-activated protein kinase kinase kinase 3 
Protein Synonyms/Alias
  
Gene Name
 MAP3K3 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
362PINWRRGKLLGQGAFubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 622 AA 
Protein Sequence
MDEQEALNSI MNDLVALQMN RRHRMPGYET MKNKDTGHSN RQSDVRIKFE HNGERRIIAF 60
SRPVKYEDVE HKVTTVFGQP LDLHYMNNEL SILLKNQDDL DKAIDILDRS SSMKSLRILL 120
LSQDRNHNSS SPHSGVSRQV RIKASQSAGD INTIYQPPEP RSRHLSVSSQ NPGRSSPPPG 180
YVPERQQHIA RQGSYTSINS EGEFIPETSE QCMLDPLSSA ENSLSGSCQS LDSPSFRKSR 240
MSRAQSFPDN RQEYSDRETQ LYDKGVKGGT YPRRYHVSVH HKDYSDGRRT FPRIRRHQGN 300
LFTLVPSSRS LSTNGENMGL AVQYLDPRGR LRSADSENAL SVQERNVPTK SPSAPINWRR 360
GKLLGQGAFG RVYLCYDVDT GRELASKQVQ FDPDSPETSK EVSALECEIQ LLKNLQHERI 420
VQYYGCLRDR AEKTLTIFME YMPGGSVKDQ LKAYGALTES VTRKYTRQIL EGMSYLHSNM 480
IVHRDIKGAN ILRDSAGNVK LGDFGASKRL QTICMSGTGM RSVTGTPYWM SPEVISGEGY 540
GRKADVWSLG CTVVEMLTEK PPWAEYEAMA AIFKIATQPT NPQLPSHISE HGRDFLRRIF 600
VEARQRPSAE ELLTHHFAQL MY 622 
Gene Ontology
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004672; F:protein kinase activity; IEA:InterPro. 
Interpro
 IPR011009; Kinase-like_dom.
 IPR000270; OPR_PB1.
 IPR000719; Prot_kinase_cat_dom.
 IPR002290; Ser/Thr_dual-sp_kinase_dom. 
Pfam
 PF00564; PB1
 PF00069; Pkinase 
SMART
 SM00666; PB1
 SM00220; S_TKc 
PROSITE
 PS50011; PROTEIN_KINASE_DOM 
PRINTS