UniProt Accession

 C9IZU3_HUMAN; C9IZU3 

Genbank Protein ID

 AC005104; AC104841 

Genbank Nucleotide ID

  

Protein Name

 Septin-2 

Protein Synonyms/Alias

  

Gene Name

 SEPT2 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
3	*****MSKQQPTQFI	ubiquitination	[1, 2, 3]

Reference

 [1] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961]
 [3] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 131 AA 

Protein Sequence

Gene Ontology

 GO:0009986; C:cell surface; IEA:Compara.
 GO:0060170; C:cilium membrane; IEA:Compara.
 GO:0000145; C:exocyst; IEA:Compara.
 GO:0048471; C:perinuclear region of cytoplasm; IEA:Compara.
 GO:0045202; C:synapse; IEA:Compara.
 GO:0030234; F:enzyme regulator activity; IEA:Compara.
 GO:0005525; F:GTP binding; IEA:InterPro.
 GO:0007049; P:cell cycle; IEA:InterPro.
 GO:0042384; P:cilium assembly; IEA:Compara.
 GO:0031175; P:neuron projection development; IEA:Compara.
 GO:0002036; P:regulation of L-glutamate transport; IEA:Compara.
 GO:0032880; P:regulation of protein localization; IEA:Compara.
 GO:0007224; P:smoothened signaling pathway; IEA:Compara. 

Interpro

 IPR000038; Cell_div_GTP-bd.
 IPR027417; P-loop_NTPase. 

Pfam

 PF00735; Septin 

SMART

  

PROSITE

  

PRINTS