CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-015588
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 40S ribosomal protein S9 
Protein Synonyms/Alias
  
Gene Name
 Rps9 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
30SRLDQELKLIGEYGLubiquitination[1]
66ELLTLDEKDPRRLFEubiquitination[1]
93VLDEGKMKLDYILGLubiquitination[1]
139QRHIRVRKQVVNIPSubiquitination[1]
155IVRLDSQKHIDFSLRacetylation[2, 3, 4, 5]
155IVRLDSQKHIDFSLRubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] SIRT5-Mediated Lysine Desuccinylation Impacts Diverse Metabolic Pathways.
 Park J, Chen Y, Tishkoff DX, Peng C, Tan M, Dai L, Xie Z, Zhang Y, Zwaans BM, Skinner ME, Lombard DB, Zhao Y.
 Mol Cell. 2013 Jun 27;50(6):919-30. [PMID: 23806337]
 [5] Quantification of mitochondrial acetylation dynamics highlights prominent sites of metabolic regulation.
 Still AJ, Floyd BJ, Hebert AS, Bingman CA, Carson JJ, Gunderson DR, Dolan BK, Grimsrud PA, Dittenhafer-Reed KE, Stapleton DS, Keller MP, Westphall MS, Denu JM, Attie AD, Coon JJ, Pagliarini DJ.
 J Biol Chem. 2013 Jul 17;. [PMID: 23864654
Functional Description
  
Sequence Annotation
 DOMAIN 108 182 S4 RNA-binding.
 MOD_RES 155 155 N6-acetyllysine (By similarity).  
Keyword
 Acetylation; Complete proteome; Cytoplasm; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 194 AA 
Protein Sequence
MPVARSWVCR KTYVTPRRPF EKSRLDQELK LIGEYGLRNK REVWRVKFTL AKIRKAAREL 60
LTLDEKDPRR LFEGNALLRR LVRIGVLDEG KMKLDYILGL KIEDFLERRL QTQVFKLGLA 120
KSIHHARVLI RQRHIRVRKQ VVNIPSFIVR LDSQKHIDFS LRSPYGGGRP GRVKRKNAKK 180
GQGGAGAGDD EEED 194 
Gene Ontology
 GO:0022627; C:cytosolic small ribosomal subunit; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0030529; C:ribonucleoprotein complex; ISS:UniProtKB.
 GO:0019843; F:rRNA binding; IEA:UniProtKB-KW.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0045182; F:translation regulator activity; IEA:Compara.
 GO:0008284; P:positive regulation of cell proliferation; IEA:Compara.
 GO:0006412; P:translation; IEA:InterPro. 
Interpro
 IPR022801; Ribosomal_S4/S9.
 IPR005710; Ribosomal_S4/S9_euk/arc.
 IPR001912; Ribosomal_S4/S9_N.
 IPR018079; Ribosomal_S4_CS.
 IPR002942; S4_RNA-bd. 
Pfam
 PF00163; Ribosomal_S4
 PF01479; S4 
SMART
 SM00363; S4 
PROSITE
 PS00632; RIBOSOMAL_S4
 PS50889; S4 
PRINTS