CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028186
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 26S proteasome regulatory complex subunit p97 
Protein Synonyms/Alias
 Regulatory particle non-ATPase 1 
Gene Name
 Rpn1 
Gene Synonyms/Alias
 CG7762; Dmel_CG7762 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
10GETKLEKKPLKPAASacetylation[1]
13KLEKKPLKPAASEGDacetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Proteasome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 919 AA 
Protein Sequence
MTGETKLEKK PLKPAASEGD AKDPKAKKDE KKDGKDKEQQ PELSDEDQQL QEELELLVQH 60
LQEPDAKLYQ PTLESMAKLI RASTTSMTSV PKPLKFMRPH YETMKTVYKH MPNEQARQLC 120
ADIISVLSMT MGSGKDCLAY RFLCDRKQRI GDWGHEYVRH LSGEISAHYH DTTGDFRVQL 180
IELVKQIIPY NMEHNAEADA CDLLIEIDHL HLLSDFVDES AYPRVCLYLQ SCYPYVPDPD 240
NTIILETALQ LSRKFNQYTQ AMRLALMLND MDKIGEIFKE PKEPAMQKQL AFMLARQQIC 300
LELDELVPDY DDLMEIMSNA NLNKHFLNLA RELDIMEPKT PEDIYKSHLD NSRSRFASIQ 360
VDSAKQNLAA SFVNGFVNAG FGVDKLLSED GNKWLYKNKE HGMLSATASL GLILLWDVDG 420
GLTMIDKYLY STDDNIKSGA LLACGIVNCG IRNEVDPAHA LLSDYIDNQN SCMRVGAILG 480
LGIAYAGSNR SIVIDTLKTV FSFGSNNKSS ASVEILGITA LSLGLISVGS CNSEITEILL 540
QTIMGLTKAD LKDTYTRFLF LGLGLLYLGR QKSTEAVMMT LEVLEEPYRS MATTMVDICA 600
YAGTGNVLKI QQLLHICSDH YETSSADDEK EKSKKDKGKD KEKEKEKEKE KEREKDLSAT 660
QSIAVLGIAL IAMGEDIGAE MAYRSFGNLL RYCEPAIRRA VPLALGLISA SNPKLNIIDT 720
LSKFSHDSDA EVAHNAIFAM GLVGAGTNNA RLASMLRQLA QYHSKDPSNL FMVRIAQSLT 780
HLGKGTLSLS PYHSDRQLMN PMAVAGLMAT LVSLLDVKNL ILNRSHYLLY TLVPAMQARM 840
LITFDEELNQ LQVPVRVGIA IDVVGQAGKP KTITGFQTHT TPVLLAIGER AELATDEYLA 900
LTPVMEGFVI LKKNPNFVK 919 
Gene Ontology
 GO:0008540; C:proteasome regulatory particle, base subcomplex; ISS:FlyBase.
 GO:0030234; F:enzyme regulator activity; IEA:InterPro.
 GO:0008283; P:cell proliferation; IMP:FlyBase.
 GO:0000022; P:mitotic spindle elongation; IMP:FlyBase.
 GO:0043161; P:proteasomal ubiquitin-dependent protein catabolic process; IC:FlyBase.
 GO:0050790; P:regulation of catalytic activity; IEA:GOC.
 GO:0042176; P:regulation of protein catabolic process; IEA:InterPro. 
Interpro
 IPR016643; 26S_Psome_Rpn1.
 IPR002015; APC_proteasome.
 IPR011989; ARM-like.
 IPR016024; ARM-type_fold. 
Pfam
 PF01851; PC_rep 
SMART
  
PROSITE
  
PRINTS