| Tag | Content |
|---|
| CPLM ID | CPLM-020492 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Ankyrin repeat and SOCS box protein 11 |
Protein Synonyms/Alias | ASB-11 |
Gene Name | Asb11 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 262 | NLRNAQGKSALDLAV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | May be a substrate-recognition component of a SCF-like ECS (Elongin-Cullin-SOCS-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins (By similarity). |
Sequence Annotation | REPEAT 64 93 ANK 1.
REPEAT 97 126 ANK 2.
REPEAT 130 159 ANK 3.
REPEAT 162 191 ANK 4.
REPEAT 195 224 ANK 5.
REPEAT 227 256 ANK 6.
REPEAT 260 289 ANK 7.
DOMAIN 273 323 SOCS box. |
Keyword | Alternative splicing; ANK repeat; Complete proteome; Reference proteome; Repeat; Ubl conjugation pathway. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 323 AA |
Protein Sequence | MEDAPAFYGF KNIFLTMFAT FFFFKLLIKV FLALLTHFYI VKGNRKEAAR IAEEIYGGLS 60
DCWADRSPLH EAAAQGRLLA LKTLIAQGIN VNLVTINRVS SLHEACLGGH VACAKALLEN 120
GAHVNAQTVH GATPLFNACC SGSAACVNVL LEFGAKAQLE IYLASPIHEA VKRGHRECME 180
ILLTKDVNIE QEVPQLGTPL YVACTYQRVD CVKKLLELGA SVDHGQWLDT PLHAAVRQSS 240
VEVINLLTVY GANLNLRNAQ GKSALDLAVP KSSVRQALLL HEGPPALSQL CRLCVRKCLG 300
RTCHHAIYAL GLPESLEKFL LYQ 323 |
Gene Ontology | GO:0035556; P:intracellular signal transduction; IEA:InterPro. GO:0016567; P:protein ubiquitination; IEA:UniProtKB-UniPathway. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |