CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-029693
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Vesicle-associated membrane protein 2 
Protein Synonyms/Alias
  
Gene Name
 Vamp2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
52IMRVNVDKVLERDQKubiquitination[1]
59KVLERDQKLSELDDRubiquitination[1]
83QFETSAAKLKRKYWWubiquitination[1]
85ETSAAKLKRKYWWKNubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Coiled coil; Complete proteome; Membrane; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 163 AA 
Protein Sequence
MSATAATVPP AAPAGEGGPP APPPNLTSNR RLQQTQAQVD EVVDIMRVNV DKVLERDQKL 60
SELDDRADAL QAGASQFETS AAKLKRKYWW KNLKMMIILG VICAIILIII IGEWGQRPGP 120
LPWGGRGFPW GAWALKVTNL VFTLQPKHTL LLLAVLTHLE PKT 163 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:InterPro.
 GO:0005886; C:plasma membrane; IDA:MGI.
 GO:0030672; C:synaptic vesicle membrane; IDA:MGI.
 GO:0070044; C:synaptobrevin 2-SNAP-25-syntaxin-1a complex; IDA:MGI.
 GO:0070032; C:synaptobrevin 2-SNAP-25-syntaxin-1a-complexin I complex; ISO:MGI.
 GO:0042589; C:zymogen granule membrane; IDA:MGI.
 GO:0005516; F:calmodulin binding; IDA:MGI.
 GO:0005543; F:phospholipid binding; IDA:MGI.
 GO:0017075; F:syntaxin-1 binding; ISO:MGI.
 GO:0017156; P:calcium ion-dependent exocytosis; IDA:MGI.
 GO:0006944; P:cellular membrane fusion; IMP:MGI.
 GO:0032869; P:cellular response to insulin stimulus; IDA:MGI.
 GO:0043001; P:Golgi to plasma membrane protein transport; IMP:MGI.
 GO:0090316; P:positive regulation of intracellular protein transport; IMP:MGI.
 GO:0017157; P:regulation of exocytosis; IDA:MGI.
 GO:0016079; P:synaptic vesicle exocytosis; IMP:MGI. 
Interpro
 IPR001388; Synaptobrevin. 
Pfam
 PF00957; Synaptobrevin 
SMART
  
PROSITE
 PS00417; SYNAPTOBREVIN
 PS50892; V_SNARE 
PRINTS
 PR00219; SYNAPTOBREVN.