UniProt Accession

 1433Z_XENLA; Q91896; O57469 

Genbank Protein ID

 X95519; AF033312 

Genbank Nucleotide ID

 CAA64773.1; AAC41252.1 

Protein Name

 14-3-3 protein zeta 

Protein Synonyms/Alias

  

Gene Name

 ywhaz 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Xenopus laevis (African clawed frog) 

NCBI Taxa ID

 8355 

Lysine Modification

Position	Peptide	Type	References
49	NLLSVAYKNVVGARR	acetylation	[1]
157	QDAFDISKTEMQPTH	acetylation	[1]
212	TLSEESYKDSTLIMQ	acetylation	[1]

Reference

 [1] A biotin switch-based proteomics approach identifies 14-3-3ζ as a target of Sirt1 in the metabolic regulation of caspase-2.
 Andersen JL, Thompson JW, Lindblom KR, Johnson ES, Yang CS, Lilley LR, Freel CD, Moseley MA, Kornbluth S.
 Mol Cell. 2011 Sep 2;43(5):834-42. [PMID: 21884983] 

Functional Description

 Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally results in the modulation of the activity of the binding partner. 

Sequence Annotation

 MOD_RES 1 1 N-acetylmethionine (By similarity).  

Keyword

 Acetylation; Cytoplasm. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 245 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell. 

Interpro

 IPR000308; 14-3-3.
 IPR023409; 14-3-3_CS.
 IPR023410; 14-3-3_domain. 

Pfam

 PF00244; 14-3-3 

SMART

 SM00101; 14_3_3 

PROSITE

 PS00796; 1433_1
 PS00797; 1433_2 

PRINTS

 PR00305; 1433ZETA.