CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041826
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 ATPase family AAA domain-containing protein 2 
Protein Synonyms/Alias
 MCG7707 
Gene Name
 Atad2 
Gene Synonyms/Alias
 mCG_7707 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1121QEQNEKLKVPCTPVAacetylation[1]
Reference
 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1364 AA 
Protein Sequence
MVVLRSSLEL HSRSTTSSAT DSLDLSSEFL SLQDSGGRRP RLRRAGRKST ASKAAGDGFT 60
VKGAETYHNT RSLRSLRNQA QTSSESSFDK NVDRTEKYSN GRHFTRQFAR QQADKKEECK 120
EDKVIPVIRS LRNRNIAPTA EHLHEQSGDV EVRRSCRIRS RYSTMNQSVL FDKLITNTAE 180
AVLQKMDDMK KMRRQRMKKL EDLGVFNETE ESNLTMYTRG KLKAIQRADE ETTDNQDGSV 240
ESSEEGEEQE DDDGEDEDDE DEEEGEEDNQ KRYYLRQRKT TVYYQSPLES KPRHQRKPNM 300
FYSGPASPAR PRFRLSSTGP RSPYCKRMSR RRHAIHSSDS TSSSSSEDDC FERRTKRNRN 360
RAINRCLPLN FRKDEIRGIY KDRMKIGASL ADVDPMQLDT SVRFDSVGGL SSHIAALKEM 420
VVFPLLYPEV FEKFKIQPPR GCLFYGPPGT GKTLVARALA NECSRGDKRV AFFMRKGADC 480
LSKWVGESER QLRLLFDQAY QMRPAIIFFD EIDGLAPVRS SRQDQIHSSI VSTLLALMDG 540
LDSRGEIVVI GATNRLDSID PALRRPGRFD REFLFSLPDK NARKEILKIH TRDWNPKPVD 600
MFLEELAEHC VGYCGADIKS ICAEAALCAL RRRYPQIYTT SEKLQLDLSS ITISAKDFEA 660
ALQKIRPASQ RAVTSPGQAL SAIVKPLLQN TVHRILDALQ KVFPHVEVGT NKSLNSDVSC 720
PFLESDLAYS DDDTPSVYEN GLSQKENLNF LHLNRNACYQ PMSFRPRLLI VGEPGFGQSS 780
HLAPAVIHAL EKFTVYTLDI PVLFGISTTS PEEACSQMIR EAKRTAPSIV YVPHIHLWWE 840
IVGPTLKATF TTLLQTIPSF APVLLLATSE KPYSALPEEV QELFTHDYGE IFNVQLPDKE 900
ERTKFFEDLI LKQASKPPVS QKKAVLQALE VLPVAPPPEP RPLTAEEVKR LEEQEEDTFR 960
ELRIFLRNVT HRLAIDKRFR VFTKPVDPDE VPDYVTVIKQ PMDLSSVISK IDLHKYLTVK 1020
DYLKDIDLIC SNALEYNPDR DPGDRLIRHR ACALRDTAYA IIKEELDEDF EQLCEEIQES 1080
RKKRGCSSSK YAPSYYHVMP KQNSPPVGDK KPDQEQNEKL KVPCTPVACS TPAQLKRKFH 1140
KKSKWHVGTK IKRRKISQAK DNSLNAMNSS SRSDTEDSQH THAEHTEPGN TDESSVEESD 1200
KQNRLESNID LKNNSSSSNI ENELEEPKET TEGTELRKDR IVCRGDASAS QVTDIPEDSE 1260
SKEMDFLRMT LARGSQVEQQ ELISMEQALA ILSQPTPSLV LDHKQLTNIL KTVVKKSQKY 1320
NIFQLENLYA VISQCIYEHR RDYDKTALVQ KMEQAVENFN CSRS 1364 
Gene Ontology
 GO:0005634; C:nucleus; IEA:Compara.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0017111; F:nucleoside-triphosphatase activity; IEA:InterPro. 
Interpro
 IPR003593; AAA+_ATPase.
 IPR003959; ATPase_AAA_core.
 IPR003960; ATPase_AAA_CS.
 IPR001487; Bromodomain.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00004; AAA
 PF00439; Bromodomain 
SMART
 SM00382; AAA
 SM00297; BROMO 
PROSITE
 PS00674; AAA
 PS50014; BROMODOMAIN_2 
PRINTS
 PR00503; BROMODOMAIN.