CPLM 1.0 - Compendium of Protein Lysine Modification
Tag
Content
CPLM ID
CPLM-041826
UniProt Accession
G3X963_MOUSE
;
G3X963
Genbank Protein ID
AC113292
;
CH466545
Genbank Nucleotide ID
EDL29297.1
Protein Name
ATPase family AAA domain-containing protein 2
Protein Synonyms/Alias
MCG7707
Gene Name
Atad2
Gene Synonyms/Alias
mCG_7707
Created Date
July 27, 2013
Organism
Mus musculus (Mouse)
NCBI Taxa ID
10090
Lysine Modification
Position
Peptide
Type
References
1121
QEQNEKL
K
VPCTPVA
acetylation
[1]
Reference
[1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [
PMID: 22826441
]
Functional Description
Sequence Annotation
Keyword
ATP-binding; Complete proteome; Nucleotide-binding; Reference proteome.
Sequence Source
UniProt (SWISSPROT/TrEMBL); GenBank; EMBL
Protein Length
1364 AA
Protein Sequence
MVVLRSSLEL HSRSTTSSAT DSLDLSSEFL SLQDSGGRRP RLRRAGRKST ASKAAGDGFT 60
VKGAETYHNT RSLRSLRNQA QTSSESSFDK NVDRTEKYSN GRHFTRQFAR QQADKKEECK 120
EDKVIPVIRS LRNRNIAPTA EHLHEQSGDV EVRRSCRIRS RYSTMNQSVL FDKLITNTAE 180
AVLQKMDDMK KMRRQRMKKL EDLGVFNETE ESNLTMYTRG KLKAIQRADE ETTDNQDGSV 240
ESSEEGEEQE DDDGEDEDDE DEEEGEEDNQ KRYYLRQRKT TVYYQSPLES KPRHQRKPNM 300
FYSGPASPAR PRFRLSSTGP RSPYCKRMSR RRHAIHSSDS TSSSSSEDDC FERRTKRNRN 360
RAINRCLPLN FRKDEIRGIY KDRMKIGASL ADVDPMQLDT SVRFDSVGGL SSHIAALKEM 420
VVFPLLYPEV FEKFKIQPPR GCLFYGPPGT GKTLVARALA NECSRGDKRV AFFMRKGADC 480
LSKWVGESER QLRLLFDQAY QMRPAIIFFD EIDGLAPVRS SRQDQIHSSI VSTLLALMDG 540
LDSRGEIVVI GATNRLDSID PALRRPGRFD REFLFSLPDK NARKEILKIH TRDWNPKPVD 600
MFLEELAEHC VGYCGADIKS ICAEAALCAL RRRYPQIYTT SEKLQLDLSS ITISAKDFEA 660
ALQKIRPASQ RAVTSPGQAL SAIVKPLLQN TVHRILDALQ KVFPHVEVGT NKSLNSDVSC 720
PFLESDLAYS DDDTPSVYEN GLSQKENLNF LHLNRNACYQ PMSFRPRLLI VGEPGFGQSS 780
HLAPAVIHAL EKFTVYTLDI PVLFGISTTS PEEACSQMIR EAKRTAPSIV YVPHIHLWWE 840
IVGPTLKATF TTLLQTIPSF APVLLLATSE KPYSALPEEV QELFTHDYGE IFNVQLPDKE 900
ERTKFFEDLI LKQASKPPVS QKKAVLQALE VLPVAPPPEP RPLTAEEVKR LEEQEEDTFR 960
ELRIFLRNVT HRLAIDKRFR VFTKPVDPDE VPDYVTVIKQ PMDLSSVISK IDLHKYLTVK 1020
DYLKDIDLIC SNALEYNPDR DPGDRLIRHR ACALRDTAYA IIKEELDEDF EQLCEEIQES 1080
RKKRGCSSSK YAPSYYHVMP KQNSPPVGDK KPDQEQNEKL KVPCTPVACS TPAQLKRKFH 1140
KKSKWHVGTK IKRRKISQAK DNSLNAMNSS SRSDTEDSQH THAEHTEPGN TDESSVEESD 1200
KQNRLESNID LKNNSSSSNI ENELEEPKET TEGTELRKDR IVCRGDASAS QVTDIPEDSE 1260
SKEMDFLRMT LARGSQVEQQ ELISMEQALA ILSQPTPSLV LDHKQLTNIL KTVVKKSQKY 1320
NIFQLENLYA VISQCIYEHR RDYDKTALVQ KMEQAVENFN CSRS 1364
Gene Ontology
GO:0005634
; C:nucleus; IEA:Compara.
GO:0005524
; F:ATP binding; IEA:UniProtKB-KW.
GO:0017111
; F:nucleoside-triphosphatase activity; IEA:InterPro.
Interpro
IPR003593
; AAA+_ATPase.
IPR003959
; ATPase_AAA_core.
IPR003960
; ATPase_AAA_CS.
IPR001487
; Bromodomain.
IPR027417
; P-loop_NTPase.
Pfam
PF00004
; AAA
PF00439
; Bromodomain
SMART
SM00382
; AAA
SM00297
; BROMO
PROSITE
PS00674
; AAA
PS50014
; BROMODOMAIN_2
PRINTS
PR00503
; BROMODOMAIN.