UniProt Accession

 SELH_HUMAN; Q8IZQ5; Q8N672 

Genbank Protein ID

 AF536829; BC021122 

Genbank Nucleotide ID

 AAN61472.1; AAH21122.2 

Protein Name

 Selenoprotein H 

Protein Synonyms/Alias

 SelH 

Gene Name

 SELH 

Gene Synonyms/Alias

 C11orf31 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
20	AVVAVAEKREKLANG	acetylation	[1, 2, 3, 4]

Reference

 [1] Lysine acetylation targets protein complexes and co-regulates major cellular functions.
 Choudhary C, Kumar C, Gnad F, Nielsen ML, Rehman M, Walther TC, Olsen JV, Mann M.
 Science. 2009 Aug 14;325(5942):834-40. [PMID: 19608861]
 [2] Proteomic investigations reveal a role for RNA processing factor THRAP3 in the DNA damage response.
 Beli P, Lukashchuk N, Wagner SA, Weinert BT, Olsen JV, Baskcomb L, Mann M, Jackson SP, Choudhary C.
 Mol Cell. 2012 Apr 27;46(2):212-25. [PMID: 22424773]
 [3] Proteomic investigations of lysine acetylation identify diverse substrates of mitochondrial deacetylase sirt3.
 Sol EM, Wagner SA, Weinert BT, Kumar A, Kim HS, Deng CX, Choudhary C.
 PLoS One. 2012;7(12):e50545. [PMID: 23236377]
 [4] Integrated proteomic analysis of post-translational modifications by serial enrichment.
 Mertins P, Qiao JW, Patel J, Udeshi ND, Clauser KR, Mani DR, Burgess MW, Gillette MA, Jaffe JD, Carr SA.
 Nat Methods. 2013 Jul;10(7):634-7. [PMID: 23749302] 

Functional Description

 May be involved in a redox-related process (Potential). 

Sequence Annotation

 MOD_RES 20 20 N6-acetyllysine.
 CROSSLNK 41 44 Cysteinyl-selenocysteine (Cys-Sec);  

Keyword

 Acetylation; Complete proteome; Redox-active center; Reference proteome; Selenocysteine. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 122 AA 

Protein Sequence

Gene Ontology

 GO:0008430; F:selenium binding; IEA:InterPro.
 GO:0045454; P:cell redox homeostasis; IEA:InterPro. 

Interpro

 IPR011893; Selenoprotein_Rdx-typ.
 IPR012336; Thioredoxin-like_fold. 

Pfam

 PF10262; Rdx 

SMART

  

PROSITE

  

PRINTS