UniProt Accession

 VTI1_YEAST; Q04338; D6W022 

Genbank Protein ID

 AF006074; Z47815; BK006946 

Genbank Nucleotide ID

 AAC49745.1; CAA87819.1; DAA10096.1 

Protein Name

 t-SNARE VTI1 

Protein Synonyms/Alias

 Qb-SNARE VTI1; VPS10-interacting protein 1; Vesicle transport v-SNARE protein VTI1 

Gene Name

 VTI1 

Gene Synonyms/Alias

 YMR197C; YM9646.10C 

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
20	KTTLEQAKASLAEAP	ubiquitination	[1]
129	SNHAILQKSGDRLKD	ubiquitination	[1]
178	QADSYVDKSIKTLKT	ubiquitination	[1]
184	DKSIKTLKTMTRRLV	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 t-SNARE found in various SNARE complexes involved in multiple transport pathways. The composition of the t-SNARE complexes is specific for a limited number of v-SNAREs and therefore allows only the vesicles carrying the matching v-SNARE to fuse. 

Sequence Annotation

 DOMAIN 124 186 t-SNARE coiled-coil homology.
 MOD_RES 2 2 N-acetylserine.
 MOD_RES 110 110 Phosphoserine.
 MOD_RES 149 149 Phosphoserine.  

Keyword

 3D-structure; Acetylation; Coiled coil; Complete proteome; Direct protein sequencing; Golgi apparatus; Membrane; Phosphoprotein; Protein transport; Reference proteome; Transmembrane; Transmembrane helix; Transport. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 217 AA 

Protein Sequence

Gene Ontology

 GO:0030173; C:integral to Golgi membrane; IDA:SGD.
 GO:0031902; C:late endosome membrane; IEA:UniProtKB-SubCell.
 GO:0031201; C:SNARE complex; IPI:SGD.
 GO:0005484; F:SNAP receptor activity; IDA:SGD.
 GO:0006896; P:Golgi to vacuole transport; IMP:SGD.
 GO:0006891; P:intra-Golgi vesicle-mediated transport; IMP:SGD.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0042144; P:vacuole fusion, non-autophagic; IMP:SGD.
 GO:0006906; P:vesicle fusion; IDA:SGD. 

Interpro

 IPR010989; t-SNARE.
 IPR000727; T_SNARE_dom.
 IPR007705; Vesicle_trsprt_v-SNARE_N. 

Pfam

 PF05008; V-SNARE 

SMART

 SM00397; t_SNARE 

PROSITE

 PS50192; T_SNARE 

PRINTS