UniProt Accession

 G3P1_SALTY; P0A1P0; P24165 

Genbank Protein ID

 AE006468; M63369 

Genbank Nucleotide ID

 AAL20215.1; AAA27114.1 

Protein Name

 Glyceraldehyde-3-phosphate dehydrogenase 

Protein Synonyms/Alias

 GAPDH 

Gene Name

 gapA 

Gene Synonyms/Alias

 gap; STM1290 

Created Date

 July 27, 2013 

Organism

 Salmonella typhimurium (strain LT2 / SGSC1412 / ATCC 700720) 

NCBI Taxa ID

 99287 

Lysine Modification

Position	Peptide	Type	References
321	NETGYSNKVLDLIAH	acetylation	[1]

Reference

 [1] Regulation of cellular metabolism by protein lysine acetylation.
 Zhao S, Xu W, Jiang W, Yu W, Lin Y, Zhang T, Yao J, Zhou L, Zeng Y, Li H, Li Y, Shi J, An W, Hancock SM, He F, Qin L, Chin J, Yang P, Chen X, Lei Q, Xiong Y, Guan KL.
 Science. 2010 Feb 19;327(5968):1000-4. [PMID: 20167786] 

Functional Description

  

Sequence Annotation

 NP_BIND 12 13 NAD (By similarity).
 REGION 149 151 Glyceraldehyde 3-phosphate binding (By
 REGION 209 210 Glyceraldehyde 3-phosphate binding (By
 ACT_SITE 150 150 Nucleophile (By similarity).
 BINDING 34 34 NAD (By similarity).
 BINDING 78 78 NAD; via carbonyl oxygen (By similarity).
 BINDING 180 180 Glyceraldehyde 3-phosphate (By
 BINDING 232 232 Glyceraldehyde 3-phosphate (By
 BINDING 314 314 NAD (By similarity).  

Keyword

 Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 331 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
 GO:0004365; F:glyceraldehyde-3-phosphate dehydrogenase (NAD+) (phosphorylating) activity; IEA:EC.
 GO:0051287; F:NAD binding; IEA:InterPro.
 GO:0050661; F:NADP binding; IEA:InterPro.
 GO:0006096; P:glycolysis; IEA:UniProtKB-UniPathway. 

Interpro

 IPR020831; GlycerAld/Erythrose_P_DH.
 IPR020830; GlycerAld_3-P_DH_AS.
 IPR020829; GlycerAld_3-P_DH_cat.
 IPR020828; GlycerAld_3-P_DH_NAD(P)-bd.
 IPR006424; Glyceraldehyde-3-P_DH_1.
 IPR016040; NAD(P)-bd_dom. 

Pfam

 PF02800; Gp_dh_C
 PF00044; Gp_dh_N 

SMART

 SM00846; Gp_dh_N 

PROSITE

 PS00071; GAPDH 

PRINTS

 PR00078; G3PDHDRGNASE.