| Tag | Content |
|---|
| CPLM ID | CPLM-001038 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Dolichol-phosphate mannosyltransferase |
Protein Synonyms/Alias | Dolichol-phosphate mannose synthase; DPM synthase; Dolichyl-phosphate beta-D-mannosyltransferase; Mannose-P-dolichol synthase; MPD synthase |
Gene Name | Dpm1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 240 | DRVYGESKLGGNEIV | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Transfers mannose from GDP-mannose to dolichol monophosphate to form dolichol phosphate mannose (Dol-P-Man) which is the mannosyl donor in pathways leading to N-glycosylation, glycosyl phosphatidylinositol membrane anchoring, and O- mannosylation of proteins. |
Sequence Annotation | MOD_RES 2 2 N-acetylalanine (By similarity).
MOD_RES 9 9 Phosphoserine (By similarity). |
Keyword | Acetylation; Complete proteome; Endoplasmic reticulum; Glycosyltransferase; Phosphoprotein; Reference proteome; Transferase. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 260 AA |
Protein Sequence | MASTGASRSL AASPRPPQGR SSRQDKYSVL LPTYNERENL PLIVWLLVKS FSESAINYEI 60
IIIDDGSPDG TREVAEQLAE IYGPDRILLR PREKKLGLGT AYIHGIKHAT GNYVIIMDAD 120
LSHHPKFIPE FIRKQKEGNF DIVSGTRYKG NGGVYGWDLK RKIISRGANF ITQILLRPGA 180
SDLTGSFRLY RKEVLQKLIE KCVSKGYVFQ MEMIVRARQM NYTIGEVPIS FVDRVYGESK 240
LGGNEIVSFL KGLLTLFATT 260 |
Gene Ontology | GO:0033185; C:dolichol-phosphate-mannose synthase complex; IEA:Compara. GO:0005789; C:endoplasmic reticulum membrane; ISS:HGNC. GO:0043178; F:alcohol binding; IEA:Compara. GO:0004582; F:dolichyl-phosphate beta-D-mannosyltransferase activity; ISS:HGNC. GO:0004169; F:dolichyl-phosphate-mannose-protein mannosyltransferase activity; ISS:HGNC. GO:0005537; F:mannose binding; IEA:Compara. GO:0019348; P:dolichol metabolic process; IMP:MGI. GO:0019673; P:GDP-mannose metabolic process; IEA:Compara. GO:0006506; P:GPI anchor biosynthetic process; ISS:HGNC. GO:0035269; P:protein O-linked mannosylation; ISS:HGNC. |
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