CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-024657
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Centrosome and spindle pole associated protein 1 
Protein Synonyms/Alias
  
Gene Name
 Cspp1 
Gene Synonyms/Alias
 Cspp 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
177EPKSQRNKNPISQGKacetylation[1]
1131RLTEQQKKPTNTDDEubiquitination[2]
Reference
 [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns.
 Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV.
 Cell Rep. 2012 Aug 30;2(2):419-31. [PMID: 22902405]
 [2] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
 May play a role in cell-cycle-dependent microtubule organization (By similarity). 
Sequence Annotation
 MOD_RES 915 915 Phosphoserine (By similarity).  
Keyword
 Alternative splicing; Coiled coil; Complete proteome; Cytoplasm; Cytoskeleton; Microtubule; Phosphoprotein; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1205 AA 
Protein Sequence
MADSLDEFIE EQKAKLAKDK AELESDPPYM EMKGKASEKL SENSKILISM AKENIPPSSQ 60
QQPKGPLGIE YGLSLPLGED YEQKKHKLKE ELRQDYRRYL TQGITQAKRK KNFLSTGETD 120
PSTLGVSLPI DERLSAKERL KLERNREYNQ FLRGKAESTE KVRQVEKNIE PKSQRNKNPI 180
SQGKSDLPLQ IQTAYTHSEG PWLSRQEEGL YRQLDGEIEL RSRRPLKQTK EEVGISGAEH 240
PSLSGSAGVP ERRARRANGE RVLDRQHCRA DRDPGVSEDM DERFRFESDF DRRLLRVYTN 300
GRPHGSRRGY VDGDDVPEEP NTQISAAENK SVHCNGPPRS ADLDITSPFA GMLFGGEDRE 360
LTKRRKEKYR QELLEQIAEQ QKKKRREKDL AFGITTSGVQ DPEKSPDRLK QFSLTPRHFE 420
EMPPERPRVA FQTPPPPFSA PSSPSVPPVH SAPSHNEDLH SGLGSTLGEL AHPRVLPVPL 480
NPPPPPLLAP PASNYRTPYD DAYYFYGARN TLDPNIVYYG SGMIGGQPAP HVSAPVTHQV 540
APPAVNTVGQ NEQKVLSDGL RNSGLVFEDK PKPSTQSLQS YQEALQEQIR EREARRKKER 600
LEKEEYEAKL EAEMRIYNPW GKGGGGAPLR DAKGNLITDL NRMHRQNIDA YHNPDARTYE 660
DKRAVVSIDQ NLATSNAENL EDSANKNSGP LQTQSSPFAR GNTFGEPLSE LQIKQQELYK 720
NFLRFQIEEK RQREEAEREK LRVAEEKEEK RLAEQRARIQ QEYEEEQERR REKEEEQRLK 780
NEELIRLAEE RRKEAERKKK EEEEKHNLQL QHYYERENII GDETKHLRQP SPVVPALQNK 840
IASKLQRPPS VDTIISSFIH ESSMSRAQSP PVPARKNQLR AEEEKKNVIM ELSEMRKQLR 900
SEERRLQGRL LHLDSDDEIP MRKRERNPMD IFDMARHRVQ APVRRPSPKG LDATTFQNIH 960
DFNELRERDS DTRVDLRLMY PDPPRDHHTL EIQQQALLRE QQKRLNRIKM RRDAGADLDT 1020
ICTDNAQGRR MPRDDTNDFL KNSLLESDSA FIGAYGETYP VIEDNAFPPP SQLPSARERR 1080
RNKLKGLDFD SSRLHTPQDG LSLKSISSVN VDQVRMRNED RMRRLTEQQK KPTNTDDEGS 1140
LVDPDDIMRH LSDDGRNSAA TEPWLRPGTS ESLKRFMAEH LNEEQHKGPG KPGTFTWQGL 1200
SAAHA 1205 
Gene Ontology
 GO:0005813; C:centrosome; ISS:UniProtKB.
 GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0000922; C:spindle pole; IDA:UniProtKB.
 GO:0032467; P:positive regulation of cytokinesis; ISS:UniProtKB. 
Interpro
 IPR026708; CSPP1. 
Pfam
  
SMART
  
PROSITE
  
PRINTS