CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-034538
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Annexin 
Protein Synonyms/Alias
  
Gene Name
 Anxa11 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
212EVLRKAMKGFGTDEQubiquitination[1]
250AYGKDLIKDLKSELSubiquitination[1]
269KTILALMKTPVLFDVubiquitination[1]
313RELSRAYKTEFQKTLubiquitination[1]
376RLGTDESKFNAILCSacetylation[2]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023]
 [2] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 
Functional Description
  
Sequence Annotation
  
Keyword
 Annexin; Calcium; Calcium/phospholipid-binding; Complete proteome; Reference proteome; Repeat. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 447 AA 
Protein Sequence
MSYPGYPPPA GGYPPAAPGG GPWGGAGYPP PSMPPIGLDN VANYAGQFNQ DYLSGMAANM 60
SGTFGGANVP NLYPGAPGGG YPPVPPGGFG QPPPAQQPVP PYGMYPPPGG NPPPGMPSYP 120
AYPGAPVPGQ PMPPTGQQPP GAYPGQPPMT YPGQSPMPPP GQQPVPSYPG YSGSSTITPA 180
VPPAQFGNRG TITAASGFDP LRDAEVLRKA MKGFGTDEQA IIDCLGSRSN KQRQQILLSF 240
KTAYGKDLIK DLKSELSGNF EKTILALMKT PVLFDVYEIK EAIKGAGTDE ACLIEIFASR 300
SNEHIRELSR AYKTEFQKTL EEAIRSDTSG HFQRLLISLS QGNRDESTNV DMSLVQRDVQ 360
ELYAAGENRL GTDESKFNAI LCSRSRAHLV AGTTVLGQLD ESRQDIVLRK SLQDICLMCS 420
GWTFTSSRAP WWCLKGQGKE MDCHALK 447 
Gene Ontology
 GO:0005737; C:cytoplasm; IDA:MGI.
 GO:0005509; F:calcium ion binding; IDA:MGI.
 GO:0005544; F:calcium-dependent phospholipid binding; IDA:MGI.
 GO:0008429; F:phosphatidylethanolamine binding; IDA:MGI. 
Interpro
 IPR001464; Annexin.
 IPR018502; Annexin_repeat.
 IPR018252; Annexin_repeat_CS.
 IPR008157; AnnexinXI. 
Pfam
 PF00191; Annexin 
SMART
 SM00335; ANX 
PROSITE
 PS00223; ANNEXIN 
PRINTS
 PR00196; ANNEXIN.
 PR01810; ANNEXINXI.