| Tag | Content |
|---|
| CPLM ID | CPLM-016099 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | TBC1 domain family member 5 |
Protein Synonyms/Alias | |
Gene Name | Tbc1d5 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 168 | SMIEQDVKRTFPEMQ | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May act as a GTPase-activating protein for Rab family protein(s). |
Sequence Annotation | DOMAIN 81 359 Rab-GAP TBC.
MOD_RES 546 546 Phosphoserine.
MOD_RES 565 565 Phosphoserine.
MOD_RES 568 568 Phosphoserine.
MOD_RES 811 811 Phosphoserine (By similarity). |
Keyword | Complete proteome; GTPase activation; Phosphoprotein; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 815 AA |
Protein Sequence | MYKSVSETRH PLQSEEQEVG IDPLFSYSNK TRGDLSQNGR GSNSTLDTEG TFNSYMKEWE 60
ELFVNNNYLA TVRQKGINGQ LRSSRFRSIC WKLFLCVLPQ DKSQWISKIK ELRAWYSSIK 120
EIHITNPRKA AGQQDLMINN PLSQDEGSLW NKFFQDKELR SMIEQDVKRT FPEMQFFQQE 180
NVRKILTDVL FCYARENEQL LYKQGMHELL APIIFTLHCD HQAFLHASES AQPSEEMKTL 240
LNPEYLEHDA YAMFSQLMET AEPWFSTFEH DGQKGKETLM APIPFARPQD LGPTVAIVTK 300
VNQIQDHLLK KHDIELYMHL NRLEIAPQIY GLRWVRLLFG REFPLQDLLV VWDALFADSL 360
NLSLVDYVFT AMLLYIRDAL ISSNYQTCLG LLMHYPIIGD IHSLILKALF LRDPKRNPRP 420
ATYQFHPNLD YYKARGADLM NKSRTNARGA PLNIHKVSNS LINFGRKLIS PASAPGSMGG 480
PVPGNNSSSS FSAAIPTRTS TEAPRHHLLQ QQQQQQHQQQ QQQQPQQQQQ QHQQQQQQQR 540
LMKSESMPVQ LNKGQSSKTI SSSPSIESLP GGREFTGSPP PSATKKDSFF SNIARSRSHS 600
KTMGRKESEE ELEAQISFLQ GQLNDLDAMC KYCAKVMDMH LVNIQDVVLQ ENLEKEDQIL 660
VSLAGLKQIK DILKGSLRFN QSQLEAGENE QITIADDHYC SSGQDQGSQV PRAAKQASSE 720
MPGCTGGTTP DDFILVSKED EGHRARGAFS GQAQPLLTLR STSGKSRAPA CSPLLFSDPL 780
MGPASASASS SNPSSSPDDD SSKESGFTIV SPLDI 815 |
Gene Ontology | GO:0005622; C:intracellular; IEA:InterPro. GO:0030904; C:retromer complex; IEA:Compara. GO:0005097; F:Rab GTPase activator activity; IEA:InterPro. GO:0032851; P:positive regulation of Rab GTPase activity; IEA:GOC. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |