| Tag | Content |
|---|
| CPLM ID | CPLM-016593 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Putative E3 ubiquitin-protein ligase UBR7 |
Protein Synonyms/Alias | N-recognin-7 |
Gene Name | Ubr7 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 384 | NDLKTELKDYLKRFA | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | E3 ubiquitin-protein ligase which is a component of the N-end rule pathway. Recognizes and binds to proteins bearing specific N-terminal residues that are destabilizing according to the N-end rule, leading to their ubiquitination and subsequent degradation (By similarity). |
Sequence Annotation | ZN_FING 44 116 UBR-type.
ZN_FING 132 188 PHD-type; atypical. |
Keyword | Complete proteome; Ligase; Metal-binding; Reference proteome; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 425 AA |
Protein Sequence | MAGAESPTEC QAELEPVVSL VDVLEEDEEL ENEACAVLGG SDSEKCSYSQ GSVGRQALYA 60
CSTCTPEGEE PAGICLACSY ECHGSHKLFE LYTKRNFRCD CGNSKFKNLE CKLFPDKSKV 120
NSCNKYNDNF FGLYCVCKRP YPDPEDEVPD EMIQCVVCED WFHGRHLGAI PPESGDFQEM 180
VCQACMRRCS FLWAYAAQLA VTRISAEDDG LLPNATGMGD EDVSKPENGA PQDNGLKEDA 240
PEHGRDSVNE VKAEQKNEPC SSSSSESDLQ TVFKKENIKT EPQSSCRLQE LQAKQFVKKD 300
AATYWPLNWR SKLCTCQDCM KMYGELDVLF LTDECDTVLA YENKGKNDQA TDRRDPLMDT 360
LSSMNRVQQV ELICEYNDLK TELKDYLKRF ADEGTVVKRE DIQQFFEEFQ SKKRRRVDGL 420
QYYCS 425 |
Gene Ontology | GO:0004842; F:ubiquitin-protein ligase activity; IEA:InterPro. GO:0008270; F:zinc ion binding; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |