CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-044061
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Kinesin-like protein KIF18B 
Protein Synonyms/Alias
  
Gene Name
 KIF18B 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
53DGGFPGLKWGGTHDGubiquitination[1, 2]
66DGPKKKGKDLTFVFDubiquitination[2]
313SKLTRLLKDSLGGNCubiquitination[2]
343EDTYNTLKYADRAKEubiquitination[2]
386EVAALRKKLQVYEGGubiquitination[2]
522RSKQLALKVLCVAQRubiquitination[2]
679SQGPSTPKGERASSPubiquitination[1]
774LFTMKGPKPTSSLPGubiquitination[1]
786LPGTSACKKKRVASSubiquitination[1]
787PGTSACKKKRVASSSubiquitination[1]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
  
Sequence Annotation
  
Keyword
 ATP-binding; Complete proteome; Microtubule; Motor protein; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 855 AA 
Protein Sequence
MAVEDSTLQV VVRVRPPTPR ELDSQRRPVV QVVDERVLVF NPEEPDGGFP GLKWGGTHDG 60
PKKKGKDLTF VFDRVFGEAA TQQDVFQHTT HSVLDSFLQG YNCSVFAYGA TGAGKTHTML 120
GREGDPGIMY LTTVELYRRL EARQQEKHFE VLISYQEVYN EQIHDLLEPK GPLAIREDPD 180
KGVVVQGLSF HQPASAEQLL EILTRGNRNR TQHPTDANAT SSRSHAIFQI FVKQQDRVPG 240
LTQAVQVAKM SLIDLAGSER ASSTHAKGER LREGANINRS LLALINVLNA LADAKGRKTH 300
VPYRDSKLTR LLKDSLGGNC RTVMIAAISP SSLTYEDTYN TLKYADRAKE IRLSLKSNVT 360
SLDCHISQYA TICQQLQAEV AALRKKLQVY EGGGQPPPQD LPGSPKSGPP PEHLPSSPLP 420
PHPPSQPCTP ELPAGPRALQ EESLGMEAQV ERAMEGNSSD QEQSPEDEDE GPAEEVPTQM 480
PEQNPTHALP ESPRLTLQPK PVVGHFSARE LDGDRSKQLA LKVLCVAQRQ YSLLQAANLL 540
TPDMITEFET LQQLVQEEKI EPGAEALRTS GLARGAPLAQ ELCSESKPPG YTGPVTRTMA 600
RRLSGPLHTL GIPPGPNCTP AQGSRWPMEK KRRRPSALEA DSPMAPKRGT KRQRQSFLPC 660
LRRGSLPDTQ PSQGPSTPKG ERASSPCHSP RVCPATVIKS RVPLGPSAMQ NCSTPLALPT 720
RDLNATFDLS EEPPSKPSFH ECIGWDKIPQ ELSRLDQPFI PRAPVPLFTM KGPKPTSSLP 780
GTSACKKKRV ASSSVSHGRS RIARLPSSTL KRPAGPLVLP ELPLSPLCPS NRRNGKDLIR 840
VGRALSAGNG VTKVS 855 
Gene Ontology
 GO:0005874; C:microtubule; IEA:UniProtKB-KW.
 GO:0005875; C:microtubule associated complex; IEA:InterPro.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003777; F:microtubule motor activity; IEA:InterPro.
 GO:0007018; P:microtubule-based movement; IEA:InterPro. 
Interpro
 IPR019821; Kinesin_motor_CS.
 IPR001752; Kinesin_motor_dom.
 IPR027417; P-loop_NTPase. 
Pfam
 PF00225; Kinesin 
SMART
 SM00129; KISc 
PROSITE
 PS00411; KINESIN_MOTOR_DOMAIN1
 PS50067; KINESIN_MOTOR_DOMAIN2 
PRINTS
 PR00380; KINESINHEAVY.