| Tag | Content |
|---|
| CPLM ID | CPLM-022481 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | JNK1/MAPK8-associated membrane protein |
Protein Synonyms/Alias | JKAMP; JNK1-associated membrane protein; JAMP; Medulloblastoma antigen MU-MB-50.4 |
Gene Name | JKAMP |
Gene Synonyms/Alias | C14orf100; JAMP; CDA06; HSPC213; HSPC327 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 16 | CLGLYCGKTLLFKNG | ubiquitination | [1] | | 185 | KIACGLGKSDRFKSI | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity). |
Sequence Annotation | |
Keyword | Alternative splicing; Complete proteome; Endoplasmic reticulum; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Ubl conjugation; Unfolded protein response. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 326 AA |
Protein Sequence | MAVDIQPACL GLYCGKTLLF KNGSTEIYGE CGVCPRGQRT NAQKYCQPCT ESPELYDWLY 60
LGFMAMLPLV LHWFFIEWYS GKKSSSALFQ HITALFECSM AAIITLLVSD PVGVLYIRSC 120
RVLMLSDWYT MLYNPSPDYV TTVHCTHEAV YPLYTIVFIY YAFCLVLMML LRPLLVKKIA 180
CGLGKSDRFK SIYAALYFFP ILTVLQAVGG GLLYYAFPYI ILVLSLVTLA VYMSASEIEN 240
CYDLLVRKKR LIVLFSHWLL HAYGIISISR VDKLEQDLPL LALVPTPALF YLFTAKFTEP 300
SRILSEGANG H 311 |
Gene Ontology | GO:0005789; C:endoplasmic reticulum membrane; IEA:UniProtKB-SubCell. GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0030433; P:ER-associated protein catabolic process; IDA:UniProtKB. GO:0006986; P:response to unfolded protein; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |