UniProt Accession

 B1ARB9_MOUSE; B1ARB9 

Genbank Protein ID

 AL603664 

Genbank Nucleotide ID

  

Protein Name

 Probable ATP-dependent RNA helicase DDX5 

Protein Synonyms/Alias

  

Gene Name

 Ddx5 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Mus musculus (Mouse) 

NCBI Taxa ID

 10090 

Lysine Modification

Position	Peptide	Type	References
91	VRGHNCPKPVLNFYE	acetylation	[1]

Reference

 [1] Quantitative acetylome analysis reveals the roles of SIRT1 in regulating diverse substrates and cellular pathways.
 Chen Y, Zhao W, Yang JS, Cheng Z, Luo H, Lu Z, Tan M, Gu W, Zhao Y.
 Mol Cell Proteomics. 2012 Oct;11(10):1048-62. [PMID: 22826441] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 183 AA 

Protein Sequence

Gene Ontology

 GO:0071013; C:catalytic step 2 spliceosome; IEA:Compara.
 GO:0005730; C:nucleolus; IEA:Compara.
 GO:0005634; C:nucleus; IC:MGI.
 GO:0030529; C:ribonucleoprotein complex; ISO:MGI.
 GO:0005524; F:ATP binding; IEA:InterPro.
 GO:0004004; F:ATP-dependent RNA helicase activity; IEA:Compara.
 GO:0036002; F:pre-mRNA binding; IEA:Compara.
 GO:0003713; F:transcription coactivator activity; IEA:Compara.
 GO:0003712; F:transcription cofactor activity; IDA:MGI.
 GO:0007623; P:circadian rhythm; IMP:MGI.
 GO:0001701; P:in utero embryonic development; IMP:MGI.
 GO:0072332; P:intrinsic apoptotic signaling pathway by p53 class mediator; IEA:Compara.
 GO:0000122; P:negative regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0043517; P:positive regulation of DNA damage response, signal transduction by p53 class mediator; IEA:Compara.
 GO:0033148; P:positive regulation of intracellular estrogen receptor signaling pathway; IEA:Compara.
 GO:0045944; P:positive regulation of transcription from RNA polymerase II promoter; IEA:Compara.
 GO:0045893; P:positive regulation of transcription, DNA-dependent; IDA:MGI.
 GO:0000381; P:regulation of alternative mRNA splicing, via spliceosome; IEA:Compara.
 GO:0060765; P:regulation of androgen receptor signaling pathway; IEA:Compara.
 GO:0045069; P:regulation of viral genome replication; IEA:Compara. 

Interpro

 IPR011545; DNA/RNA_helicase_DEAD/DEAH_N.
 IPR014001; Helicase_ATP-bd.
 IPR027417; P-loop_NTPase.
 IPR014014; RNA_helicase_DEAD_Q_motif. 

Pfam

 PF00270; DEAD 

SMART

  

PROSITE

 PS51192; HELICASE_ATP_BIND_1
 PS51195; Q_MOTIF 

PRINTS