UniProt Accession

 ARFP1_HUMAN; P53367; Q2M2X4; Q3SYL4; Q9Y2X6 

Genbank Protein ID

 U52521; AF124489; AK290472; CH471056; CH471056; BC103759; BC105114; BC105116; BC143675 

Genbank Nucleotide ID

 AAA97923.1; AAD29390.1; BAF83161.1; EAX04968.1; EAX04969.1; AAI03760.1; AAI05115.1; AAI05117.1; AAI43676.1 

Protein Name

 Arfaptin-1 

Protein Synonyms/Alias

 ADP-ribosylation factor-interacting protein 1 

Gene Name

 ARFIP1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
118	VILADEIKNPAMEKL	ubiquitination	[1]
353	KQLEQTLKQFHIKLK	ubiquitination	[2]
360	KQFHIKLKTPGVDAP	ubiquitination	[3]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] A proteome-wide, quantitative survey of in vivo ubiquitylation sites reveals widespread regulatory roles.
 Wagner SA, Beli P, Weinert BT, Nielsen ML, Cox J, Mann M, Choudhary C.
 Mol Cell Proteomics. 2011 Oct;10(10):M111.013284. [PMID: 21890473]
 [3] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

 Putative target protein of ADP-ribosylation factor. 

Sequence Annotation

 DOMAIN 153 353 AH.
 MOD_RES 2 2 N-acetylalanine.
 MOD_RES 5 5 Phosphoserine.
 MOD_RES 69 69 Phosphoserine.
 MOD_RES 79 79 Phosphoserine.
 MOD_RES 132 132 Phosphoserine.
 MOD_RES 361 361 Phosphothreonine.  

Keyword

 Acetylation; Alternative splicing; Complete proteome; Phosphoprotein; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 373 AA 

Protein Sequence

Gene Ontology

 GO:0005829; C:cytosol; IDA:MGI.
 GO:0000139; C:Golgi membrane; IDA:UniProtKB.
 GO:0006886; P:intracellular protein transport; IDA:MGI.
 GO:0050708; P:regulation of protein secretion; IDA:MGI. 

Interpro

 IPR027267; AH/BAR-dom.
 IPR010504; AH_dom. 

Pfam

 PF06456; Arfaptin 

SMART

 SM01015; Arfaptin 

PROSITE

 PS50870; AH 

PRINTS