CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-002636
UniProt Accession
Genbank Protein ID
 M17018 
Genbank Nucleotide ID
Protein Name
 Histone H1.10 
Protein Synonyms/Alias
 Methylated DNA-binding protein 2-H1; MDBP-2-H1 
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Gallus gallus (Chicken) 
NCBI Taxa ID
 9031 
Lysine Modification
Position
Peptide
Type
References
91GLKSLVSKGTLVQTKacetylation[1]
170AATKKAAKSPKKATKacetylation[1]
Reference
 [1] Characterization of post-translational modifications of the linker histones H1 and H5 from chicken erythrocytes using mass spectrometry.
 Snijders AP, Pongdam S, Lambert SJ, Wood CM, Baldwin JP, Dickman MJ.
 J Proteome Res. 2008 Oct;7(10):4326-35. [PMID: 18754630] 
Functional Description
 Histones H1 are necessary for the condensation of nucleosome chains into higher-order structures. 
Sequence Annotation
 DOMAIN 37 110 H15.
 MOD_RES 2 2 N-acetylserine.  
Keyword
 Acetylation; Chromosome; Complete proteome; Direct protein sequencing; DNA-binding; Nucleus; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 220 AA 
Protein Sequence
MSETAPAAAP AVAAPAAKAA AKKPKKAAGG AKARKPAGPS VTELITKAVS ASKERKGLSL 60
AALKKALAAG GYDVEKNNSR IKLGLKSLVS KGTLVQTKGT GASGSFRLSK KPGEVKEKAP 120
RKRTPAAKPK KPAAKKPASA AKKPKKAAAA KKSPKKAKKP AAAATKKAAK SPKKATKAAK 180
PKKAATAKSP AKAKAVKPKA AKPKAAKPKA AKAKKAAAKK 220 
Gene Ontology
 GO:0000786; C:nucleosome; IEA:InterPro.
 GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
 GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
 GO:0006334; P:nucleosome assembly; IEA:InterPro. 
Interpro
 IPR005818; Histone_H1/H5.
 IPR005819; Histone_H5.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00538; Linker_histone 
SMART
 SM00526; H15 
PROSITE
 PS51504; H15 
PRINTS
 PR00624; HISTONEH5.