UniProt Accession

 KR511_HUMAN; Q6L8G4 

Genbank Protein ID

 AB126080 

Genbank Nucleotide ID

 BAD20207.1 

Protein Name

 Keratin-associated protein 5-11 

Protein Synonyms/Alias

 Keratin-associated protein 5.11; Ultrahigh sulfur keratin-associated protein 5.11 

Gene Name

 KRTAP5-11 

Gene Synonyms/Alias

 KAP5.11; KRTAP5.11 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
74	CGSCGSSKGGCGSCG	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 In the hair cortex, hair keratin intermediate filaments are embedded in an interfilamentous matrix, consisting of hair keratin-associated protein (KRTAP), which are essential for the formation of a rigid and resistant hair shaft through their extensive disulfide bond cross-linking with abundant cysteine residues of hair keratins. The matrix proteins include the high- sulfur and high-glycine-tyrosine keratins. 

Sequence Annotation

 REPEAT 35 38 1.
 REPEAT 41 44 2.
 REPEAT 47 50 3.
 REPEAT 87 90 4.
 REPEAT 121 124 5.
 REPEAT 146 149 6.
 REGION 35 149 6 X 4 AA repeats of C-C-X-P.  

Keyword

 Complete proteome; Keratin; Reference proteome; Repeat. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 156 AA 

Protein Sequence

Gene Ontology

 GO:0045095; C:keratin filament; IEA:InterPro. 

Interpro

 IPR002494; Keratin-assoc. 

Pfam

  

SMART

  

PROSITE

  

PRINTS