| Tag | Content |
|---|
| CPLM ID | CPLM-014856 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | ATP-dependent DNA helicase Q1 |
Protein Synonyms/Alias | DNA-dependent ATPase Q1; RecQ protein-like 1 |
Gene Name | Recql |
Gene Synonyms/Alias | Recql1 |
Created Date | July 27, 2013 |
Organism | Rattus norvegicus (Rat) |
NCBI Taxa ID | 10116 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 501 | QALIKILKQAEGLNE | acetylation | [1] |
|
Reference | [1] Proteomic analysis of lysine acetylation sites in rat tissues reveals organ specificity and subcellular patterns. Lundby A, Lage K, Weinert BT, Bekker-Jensen DB, Secher A, Skovgaard T, Kelstrup CD, Dmytriyev A, Choudhary C, Lundby C, Olsen JV. Cell Rep. 2012 Aug 30;2(2):419-31. [ PMID: 22902405] |
Functional Description | DNA helicase that may play a role in the repair of DNA that is damaged by ultraviolet light or other mutagens. Exhibits a magnesium-dependent ATP-dependent DNA-helicase activity that unwinds single- and double-stranded DNA in a 3'-5' direction (By similarity). |
Sequence Annotation | DOMAIN 100 275 Helicase ATP-binding.
DOMAIN 296 451 Helicase C-terminal.
NP_BIND 113 120 ATP (Potential).
MOTIF 219 222 DEVH box.
MOD_RES 514 514 N6-acetyllysine (By similarity).
MOD_RES 522 522 N6-acetyllysine (By similarity). |
Keyword | Acetylation; ATP-binding; Complete proteome; DNA-binding; Helicase; Hydrolase; Nucleotide-binding; Nucleus; Reference proteome. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 621 AA |
Protein Sequence | MASIPALTDE LESVSSELHA VDIQIQELTE RQHELLQRKS VLTKRIKQCL EDSAAEASGD 60
CDTSPAAWSK EDFPWSGKVK HVLRDVFKLQ KFRPLQLETV NATMARKDIF LVMPTGGGKS 120
LCYQLPALCS DGFTLVICPL ISLMEDQLMV LQQLGISATM LNSSSSKEHV KCVHTEMMNK 180
NSHLKLIYVT PEKIAKSKMF MSRLEKAYEA GRLTGVAVDE VHCCSQWGHD FRPDYKALGI 240
LKRQFPNISL IGLTATATNH VLKDAQKILC VEKCLTFTAS FNRPNLYYEV RQKPSSAEDF 300
IENIANLING RYKGKSGIIY CFSQKDSEQV TISLQKLGVR AGTYHANMEP EDRTKVHTQW 360
SANELQVVVA TVAFGMGIDK PDVRFVIHHS MSKSMENYYQ ESGRAGRDDW RADCILYYGF 420
GDIFRISSMV VMENVGQQKL YEMVSYCQNI SKCRRALIAQ HFDEVWNADA CNKMCDNCCK 480
DDSFEKKNIT EHCQALIKIL KQAEGLNEKL TPLKLIDAWM GKGAAKFRVA GVAVPALPRE 540
DLEKIIVHAL LQQYLKEDYS FTAYATISYL KVGPRASLLS NEGHAVTMQV KRSTQSSVRA 600
ASPEACEVDS KGKEKSSAVL C 621 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |