CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-040756
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Glycerol-3-phosphate dehydrogenase, mitochondrial 
Protein Synonyms/Alias
  
Gene Name
 GPD2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
246GLFLQGGKDWSPTLYubiquitination[1]
277LAATYGDKAFEVAKMubiquitination[1, 2]
283DKAFEVAKMASVTGKubiquitination[1]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Calcium; Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 500 AA 
Protein Sequence
MNLAIALTAA RYGAATANYM EVVSLLKKTD PQTGKVRVSG ARCKDVLTGQ EFDVRAKCVI 60
NATGPFTDSV RKMDDKDAAA ICQPSAGVHI VMPGYYSPES MGLLDPATSD GRVIFFLPWQ 120
KMTIAGTTDT PTDVTHHPIP SEEDINFILN EVRNYLSCDV EVRRGDVLAA WSGIRPLVTD 180
PKSADTQSIS RNHVVDISES GLITIAGGKW TTYRSMAEDT INAAVKTHNL KAGPSRTVGL 240
FLQGGKDWSP TLYIRLVQDY GLESEVAQHL AATYGDKAFE VAKMASVTGK RWPIVGVRLV 300
SEFPYIEAEV KYGIKEYACT AVDMISRRTR LAFLNVQAAE EALPRIVELM GRELNWDDYK 360
KQEQLETARK FLYYEMGYKS RSEQLTDRSE ISLLPSDIDR YKKRFHKFDA DQKGFITIVD 420
VQRVLESINV QMDENTLHEI LNEVDLNKNG QVELNEFLQL MSAIQKGRVS GSRLAILMKT 480
AEENLDRRVP IPVDRSCGGL 500 
Gene Ontology
 GO:0009331; C:glycerol-3-phosphate dehydrogenase complex; IEA:InterPro.
 GO:0005743; C:mitochondrial inner membrane; IEA:Compara.
 GO:0005509; F:calcium ion binding; IEA:InterPro.
 GO:0004368; F:glycerol-3-phosphate dehydrogenase activity; IEA:InterPro.
 GO:0006094; P:gluconeogenesis; IEA:Compara.
 GO:0006072; P:glycerol-3-phosphate metabolic process; IEA:Compara. 
Interpro
 IPR011992; EF-hand-like_dom.
 IPR018247; EF_Hand_1_Ca_BS.
 IPR002048; EF_hand_dom.
 IPR006076; FAD-dep_OxRdtase.
 IPR000447; G3P_DH_FAD-dep. 
Pfam
 PF01266; DAO
 PF13499; EF_hand_5 
SMART
 SM00054; EFh 
PROSITE
 PS00018; EF_HAND_1
 PS50222; EF_HAND_2
 PS00978; FAD_G3PDH_2 
PRINTS