CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-014147
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Probable cation-transporting ATPase 13A3 
Protein Synonyms/Alias
  
Gene Name
 Atp13a3 
Gene Synonyms/Alias
 Gm542 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
338PNPSVDVKGMGEEQYubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023
Functional Description
  
Sequence Annotation
 ACT_SITE 494 494 4-aspartylphosphate intermediate (By
 METAL 879 879 Magnesium (By similarity).
 METAL 883 883 Magnesium (By similarity).
 MOD_RES 813 813 Phosphoserine.  
Keyword
 Alternative splicing; ATP-binding; Complete proteome; Hydrolase; Magnesium; Membrane; Metal-binding; Nucleotide-binding; Phosphoprotein; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1219 AA 
Protein Sequence
MDKEERKTIN KGQEDEMEIH GYNLCRWKLA MVFVGVICTG GFLLLLLYWL PEWRVKATCV 60
RAAVKDCEVV LLRTTDEFRV WFCAKIHFLP VENQPNLNAK CLVNEVSNGH AVHLTEENRC 120
EMNKYSQSQS QQMRYFTHHS IRYFWNDAIH NFDFLKGLDE GVSCASLYEK HSAGLTQGMH 180
AYRKLIYGVN EIAVKVPSVF KLLIKEVLNP FYIFQLFSVI LWSVDEYYYY ALAIVIMSVV 240
SIISSLYSIR KQYVMLHDMV ATHSTVRVSV CRENEEIEEI FSTDLVPGDV MIIPLNGTVM 300
PCDAVLINGT CIVNESMLTG ESVPVTKTNL PNPSVDVKGM GEEQYSPETH KRHTLFCGTT 360
VIQTRFYTGE LVKAIVVRTG FSTSKGQLVR SILYPKPTDF KLYRDAYLFL LCLVVVAGIG 420
FIYTIINSIL NEKEVQEIII KSLDIITITV PPALPAAMTA GIVYAQRRLK KVGIFCISPQ 480
RINICGQLNL VCFDKTGTLT EDGLDLWGIQ RVENTRFLLP EDNVCSEMLV KSQFVACMAT 540
CHSLTKIEGV LSGDPLDLKM FEAIGWILEE ATEEETALHN RIMPTVVRPS KQLLPEPTTA 600
GNQEMELFEL PAIYEIGIVR QFPFSSALQR MSVVARTLGE KRMDAYMKGA PEVVASLCKP 660
ETVPVDFEKV LEDYTKQGFR VIALAHRKLE SKLTWHKVQH ISRDAIENNM DFMGLIIMQN 720
KLKQETPAVL EDLHKANIRT VMVTGDNMLT AVSVARDCGM ILPQDKVIIA EALPPKDGKV 780
AKINWHYTDS LSQCSESSAI DSEAIPIKLA HDSLEDLEVT RYHFAMNGKS FSVILEHFQD 840
LVPKLMLHGT VFARMAPDQK TQLVEALQNV DYFVGMCGDG ANDCGALKRA HGGISLSELE 900
ASVASPFTSK TPSISCVPNL IREGRAALMT SFCVFKFMAL YSIIQYFSVT LLYSILSNLG 960
DFQFLFIDLA IILVVVFTMS LNPAWKELVA QRPPSGLISG ALLFSVLSQI VISVGFQSLG 1020
FFWVKQYKVC DPNSDVCNTT RSACWNSSHL YNGTELDSCK IQNYENTTVF FISSFQYLTV 1080
AVAFSKGKPF RQPCYKNYFF VISVIILYVF ILFIMLHPVA SVDQVLEIMC VPYQWRIYML 1140
IIVLINAFVS ITVESFFLDT VLWKVVFNRD KQGECRFSTT QPPQESVDRW GKCCLSWALS 1200
CRKKTPKAKY MYLAQELRFD PEWPPKPQTT TEAKAVVKEN GSCQIITIA 1249 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0019829; F:cation-transporting ATPase activity; IEA:InterPro.
 GO:0046872; F:metal ion binding; IEA:UniProtKB-KW.
 GO:0006200; P:ATP catabolic process; IEA:GOC. 
Interpro
 IPR004014; ATPase_P-typ_cation-transptr_N.
 IPR006544; ATPase_P-typ_Cation_typ_V.
 IPR023299; ATPase_P-typ_cyto_domN.
 IPR018303; ATPase_P-typ_P_site.
 IPR008250; ATPase_P-typ_transduc_dom_A.
 IPR001757; Cation_transp_P_typ_ATPase.
 IPR023214; HAD-like_dom. 
Pfam
 PF00690; Cation_ATPase_N
 PF00122; E1-E2_ATPase
 PF12409; P5-ATPase 
SMART
 SM00831; Cation_ATPase_N 
PROSITE
 PS00154; ATPASE_E1_E2 
PRINTS
 PR00119; CATATPASE.