CPLM-019095

CPLM 1.0 - Compendium of Protein Lysine Modification

Tag

Content

CPLM ID

CPLM-019095

UniProt Accession

PTER_HUMAN; Q96BW5; B0YJ77; B3KTF5; D3DRU0; Q9BY46

Genbank Protein ID

AF212237; AK095486; AK314910; EF445015; EF445015; EF445015; AL360230; CH471072; CH471072; CH471072; CH471072; CH471072; BC015092; BC050411

Genbank Nucleotide ID

AAK14923.1; BAG53067.1; BAG37422.1; ACA06055.1; ACA06056.1; ACA06057.1; CAH73146.1; EAW86226.1; EAW86229.1; EAW86227.1; EAW86228.1; EAW86230.1; AAH15092.1; AAH50411.1

Protein Name

Phosphotriesterase-related protein

Protein Synonyms/Alias

Parathion hydrolase-related protein; hPHRP

Gene Name

PTER

Gene Synonyms/Alias

Created Date

July 27, 2013

Organism

Homo sapiens (Human)

NCBI Taxa ID

9606

Lysine Modification

Position	Peptide	Type	References
19	LGLVEPSKLGRTLTH	ubiquitination	[1]
81	NQETEAIKEELLYFK	ubiquitination	[1]
296	KILIENPKQWLTFK*	ubiquitination	[1]

Reference

[1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]

Functional Description

Sequence Annotation

METAL 26 26 Divalent metal cation 1 (By similarity).
METAL 28 28 Divalent metal cation 1 (By similarity).
METAL 169 169 Divalent metal cation 1 (By similarity).
METAL 169 169 Divalent metal cation 2 (By similarity).
METAL 201 201 Divalent metal cation 2 (By similarity).
METAL 230 230 Divalent metal cation 2 (By similarity).
METAL 298 298 Divalent metal cation 1 (By similarity).

Keyword

Alternative splicing; Complete proteome; Hydrolase; Metal-binding; Polymorphism; Reference proteome.

Sequence Source

UniProt (SWISSPROT/TrEMBL); GenBank; EMBL

Protein Length

349 AA

Protein Sequence

MSSLSGKVQT VLGLVEPSKL GRTLTHEHLA MTFDCCYCPP PPCQEAISKE PIVMKNLYWI 60
QKNAYSHKEN LQLNQETEAI KEELLYFKAN GGGALVENTT TGISRDTQTL KRLAEETGVH 120
IISGAGFYVD ATHSSETRAM SVEQLTDVLM NEILHGADGT SIKCGIIGEI GCSWPLTESE 180
RKVLQATAHA QAQLGCPVII HPGRSSRAPF QIIRILQEAG ADISKTVMSH LDRVRLLVEE 240
GCEDRILVAH DIHTKTRLMK YGGHGYSHIL TNVVPKMLLR GITENVLDKI LIENPKQWLT 300
FK 302

Gene Ontology

GO:0016788; F:hydrolase activity, acting on ester bonds; IEA:InterPro.
GO:0008270; F:zinc ion binding; IEA:InterPro.
GO:0009056; P:catabolic process; IEA:InterPro.

Interpro

IPR017947; AryldialkylPase_Zn-BS.
IPR001559; Aryldialkylphosphatase.

Pfam

PF02126; PTE

SMART

PROSITE

PS01322; PHOSPHOTRIESTERASE_1
PS51347; PHOSPHOTRIESTERASE_2

PRINTS