CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-038072
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Cullin-5 
Protein Synonyms/Alias
  
Gene Name
 Cul5 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
149EDILEFIKQAQARVLubiquitination[1]
269LCSNPEDKLQIYRDNubiquitination[1]
772EAIIQIMKMRKKISNubiquitination[1]
776QIMKMRKKISNAQLQubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 828 AA 
Protein Sequence
MRSLAWAGRG DHVAGKPEEA RLPGTSSALT ARRSGVPRIP RRGLRGPAGN PGLSRRPGPE 60
RRQVSPRLAR VQVENMATSN LLKNKGSLQF EDKWDFMHPI VLKLLRQESV TKQQWFDLFS 120
DVHAVCLWDD KGSSKIHQAL KEDILEFIKQ AQARVLSHQD DTALLKAYIV EWRKFFTQCD 180
ILPKPFCQLE VTLLGKQSSN KKSNMEDSIV RKLMLDTWNE SIFSNIKNRL QDSAMKLVHA 240
ERLGEAFDSQ LVIGVRESYV NLCSNPEDKL QIYRDNFEKA YLDSTERFYR TQAPSYLQQN 300
GVQNYMKYLM ECCVNALVTS FKETILAECQ GMIKRNETEK LHLMFSLMDK VPNGIEPMLK 360
DLEEHIISAG LADMVAAAET ITTDSEKYVE QLLTLFNRFS KLVKEAFQDD PRFLTARDKA 420
YKAVVNDATI FKLELPLKQK GVGLKTQPES KCPELLANYC DMLLRKTPLS KKLTSEEIEA 480
KLKEVLLVLK YVQNKDVFMR YHKAHLTRRL ILDISADSEI EENMVEWLRE VGMPADYVNK 540
LARMFQDIKV SEDLNQAFKE MHKNNKLALP ADSVNIKILN AGAWSRSSEK VFVSLPTELE 600
DLIPEVEEFY KKNHSGRKLH WHHLMSNGII TFKNEVGQYD LEVTTFQLAV LFAWNQRPRE 660
KISFENLKLA TELPDAELRR TLWSLVAFPK LKRQVLLYDP QVNSPKDFTE GTLFSVNQDF 720
SLIKNAKVQK RGKINLIGRL QLTTERMREE ENEGIVQLRI LRTQEAIIQI MKMRKKISNA 780
QLQTELVEIL KNMFLPQKKM IKEQMEWLIE HRYIRRDEAD INTFIYMA 828 
Gene Ontology
 GO:0031461; C:cullin-RING ubiquitin ligase complex; IEA:InterPro.
 GO:0006511; P:ubiquitin-dependent protein catabolic process; IEA:InterPro. 
Interpro
 IPR016157; Cullin_CS.
 IPR016158; Cullin_homology.
 IPR001373; Cullin_N.
 IPR019559; Cullin_neddylation_domain.
 IPR016159; Cullin_repeat-like_dom.
 IPR011991; WHTH_DNA-bd_dom. 
Pfam
 PF00888; Cullin
 PF10557; Cullin_Nedd8 
SMART
 SM00182; CULLIN
 SM00884; Cullin_Nedd8 
PROSITE
 PS01256; CULLIN_1
 PS50069; CULLIN_2 
PRINTS