| Tag | Content |
|---|
| CPLM ID | CPLM-024816 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Alpha-tubulin |
Protein Synonyms/Alias | |
Gene Name | tuba1b |
Gene Synonyms/Alias | tuba1 |
Created Date | July 27, 2013 |
Organism | Danio rerio (Zebrafish) (Brachydanio rerio) |
NCBI Taxa ID | 7955 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 40 | DGQMPSDKTIGGGDD | acetylation | [1] |
|
Reference | [1] MEC-17 is an alpha-tubulin acetyltransferase. Akella JS, Wloga D, Kim J, Starostina NG, Lyons-Abbott S, Morrissette NS, Dougan ST, Kipreos ET, Gaertig J. Nature. 2010 Sep 9;467(7312):218-22. [ PMID: 20829795] |
Functional Description | Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain (By similarity). |
Sequence Annotation | |
Keyword | Cytoplasm; Cytoskeleton; GTP-binding; Microtubule; Nucleotide-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 449 AA |
Protein Sequence | MRECISIHVG QAGVQIGNAC WELYCLEHGI QPDGQMPSDK TIGGGDDSFN TFFSETGAGK 60
HVPRAVFVDL EPTVIDEVRT GTYRQLFHPE QLITGKEDAA NNYARGHYTI GKELIDLVLD 120
RVRKLSDQCT GLQGFLVFHS FGGGTGSGFT SLLMERLSVD YGKKSKLEFS IYPAPQVSTA 180
VVEPYNSILT THTTLEHSDC AFMVDNEAIY DICRRNLDIE RPTYTNLNRL ISQIVSSITA 240
SLRFDGALNV DLTEFQTNLV PYPRIHFPLA TYAPVISAEK AYHEQLSVAE ITNACFEPAN 300
QMVKCDPRHG KYMACCLLYR GDVVPKDVNA AIATIKTKRT IQFVDWCPTG FKVGINYQPP 360
TVVPGGDLAK VQRAVCMLSN TTAIAEAWAR LDHKFDLMYA KRAFVHWYVG EGMEEGEFSE 420
AREDMAALEK DYEEVGAESV EGEDEGEEY 449 |
Gene Ontology | GO:0005737; C:cytoplasm; IEA:UniProtKB-KW. GO:0005874; C:microtubule; IEA:UniProtKB-KW. GO:0005525; F:GTP binding; IEA:UniProtKB-KW. GO:0003924; F:GTPase activity; IEA:InterPro. GO:0005200; F:structural constituent of cytoskeleton; IEA:InterPro. GO:0007017; P:microtubule-based process; IEA:InterPro. GO:0051258; P:protein polymerization; IEA:InterPro. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |