| Tag | Content |
|---|
| CPLM ID | CPLM-000874 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | E3 ubiquitin-protein ligase Praja-1 |
Protein Synonyms/Alias | Praja1 |
Gene Name | Pja1 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 351 | SWELLPGKEELERQQ | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Has E2-dependent E3 ubiquitin-protein ligase activity. Ubiquitinates MAGED1 antigen leading to its subsequent degradation by proteasome. May be involved in protein sorting. |
Sequence Annotation | ZN_FING 530 571 RING-type.
MOD_RES 231 231 Phosphothreonine. |
Keyword | Alternative splicing; Complete proteome; Ligase; Metal-binding; Phosphoprotein; Reference proteome; Ubl conjugation; Ubl conjugation pathway; Zinc; Zinc-finger. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 578 AA |
Protein Sequence | MSHQERIASQ RRTTAEVPMH RSTANQSKRS RSPFASTRRR WDDSESSGAS LAVESEDYSR 60
YPPREYRASG SRRGLAYGHI DTVVARDSEE EGAGPVDRLP VRGKAGKFKD DPEKGARSSR 120
FTSVNHDAKE ECGKVESPPA ARCSARRAEL SKQNGSSASQ ISSAEGRAAA KGNNSLERER 180
QNLPARPSRA PVSICGGGEN TPKSAEEPVV RPKVRNVATP NCMKPKVFFD TDDDDDVPHS 240
TSRWRDAADA EEAHAEGLAR RGRGEAASSS EPRYAEDQDA RSEQAKADKV PRRRRTMADP 300
DFWAYTDDYY RYYEEDSDSD KEWMAALRRK YRSREQPQSS SGESWELLPG KEELERQQAG 360
AGSLASAGSN GSGYPEEVQD PSLQEEEQAS LEEGEIPWLR YNENESSSEG DNESTHELIQ 420
PGMFMLDGNN NLEDDSSVSE DLEVDWSLFD GFADGLGVAE AISYVDPQFL TYMALEERLA 480
QAMETALAHL ESLAVDVEVA NPPASKESID ALPEILVTED HGAVGQEMCC PICCSEYVKG 540
EVATELPCHH YFHKPCVSIW LQKSGTCPVC RCMFPPPL 578 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |