CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028417
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Brain-specific angiogenesis inhibitor 2 
Protein Synonyms/Alias
  
Gene Name
 BAI2 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
489AGEIIYNKCPPNASGubiquitination[1]
Reference
 [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961
Functional Description
  
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1466 AA 
Protein Sequence
MTPACPLLLS VILSLRLATA FDPAPSACSA LASGVLYGAF SLQDLFPTIA SGCSWTLENP 60
DPTKYSLYLR FNRQEQVCAH FAPRLLPLDH YLVNFTCLRP SPEEAVAQAE SEVGRPEEEE 120
AEAAAGLELC SGSGPFTFLH FDKNFVQLCL SAEPSEAPRL LAPAALAFRF VEVLLINNNN 180
SSQFTCGVLC RWSEECGRAA GRACGFAQPG CSCPGEAGAG STTTTSPGPP AAHTLSNALV 240
PGGPAPPAEA DLHSGSSNDL FTTEMRYGEE PEEEPKVKTQ WPRSADEPGL YMAQTGDPAA 300
EEWSPWSVCS LTCGQGLQVR TRSCVSSPYG TLCSGPLRET RPCNNSATCP VEGQWLEWGP 360
WGPCSTSCAN GTQQRSRKCS VAGPAWATCT GALTDTRECS NLECPATDSK WGPWNAWSLC 420
SKTCDTGWQR RFRMCQATGT QGYPCEGTGE EVKPCSEKRC PAFHEMCRDE YVMLMTWKKA 480
AAGEIIYNKC PPNASGSASR RCLLSAQGVA YWGLPSFARC ISHEYRYLYL SLREHLAKGQ 540
RMLAGEGMSQ VVRSLQELLA RRTYYSGDLL FSVDILRNVT DTFKRATYVP SADDVQRFFQ 600
VVSFMVDAEN KEKWDDAQQV SPGSVHLLRV VEDFIHLVGD ALKAFQSSLI VTDNLVISIQ 660
REPVSAVSSD ITFPMRGRRG MKDWVRHSED RLFLPKEVLS LSSPGKPATS GAAGSPGRGR 720
GPGTVPPGPG HSHQRLLPAD PDESSYFVIG AVLYRTLGLI LPPPRPPLAV TSRVMTVTVR 780
PPTQPPAEPL ITVELSYIIN GTTDPHCASW DYSRADASSG DWDTENCQTL ETQAAHTRCQ 840
CQHLSTFAVL AQPPKDLTLE LAGSPSVPLV IGCAVSCMAL LTLLAIYAAF WRFIKSERSI 900
ILLNFCLSIL ASNILILVGQ SRVLSKGVCT MTAAFLHFFF LSSFCWVLTE AWQSYLAVIG 960
RMRTRLVRKR FLCLGWGLPA LVVAVSVGFT RTKGYGTSSY CWLSLEGGLL YAFVGPAAVI 1020
VLVNMLIGII VFNKLMARDG ISDKSKKQRA GASLWSSCVV LPLLALTWMS AVLAMTDRRS 1080
VLFQALFAVF NSAQGFVITA VHCFLRREVQ DVVKCQMGVC RADESEDSPD SCKNGQLQIL 1140
SDFEKDVDLA CQTVLFKEVN TCNPSTITGT LSRLSLDEDE EPKSCLVGPE GSLSFSPLPG 1200
NILVPMAASP GLGEPPPPQE ANPVYMCGEG GLRQLDLTWL RPTEPGSEGD YMVLPRRTLS 1260
LQPGGGGGGG EDAPRARPEG TPRRAAKTVA HTEGYPSFLS VDHSGLGLGP AYGSLQNPYG 1320
MTFQPPPPTP SARQVPEPGE RSRTMPRTVP GSTMKMGSLE RKKLRYSDLD FEKVMHTRKR 1380
HSELYHELNQ KFHTFDRYRS QSTAKDKPSP GERPSLSQHR RHQSWSTFKS MTLGSLPPKP 1440
RERLTLHRAA AWEPTEPPDG DFQTEV 1466 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
 GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro.
 GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. 
Interpro
 IPR022624; DUF3497.
 IPR017981; GPCR_2-like.
 IPR008077; GPCR_2_brain-spec_angio_inhib.
 IPR001879; GPCR_2_extracellular_dom.
 IPR000832; GPCR_2_secretin-like.
 IPR000203; GPS_dom.
 IPR000884; Thrombospondin_1_rpt. 
Pfam
 PF00002; 7tm_2
 PF12003; DUF3497
 PF01825; GPS
 PF02793; HRM
 PF00090; TSP_1 
SMART
 SM00303; GPS
 SM00008; HormR
 SM00209; TSP1 
PROSITE
 PS50227; G_PROTEIN_RECEP_F2_3
 PS50261; G_PROTEIN_RECEP_F2_4
 PS50221; GPS
 PS50092; TSP1 
PRINTS
 PR01694; BAIPRECURSOR.
 PR00249; GPCRSECRETIN.