CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025702
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Precorrin-3 C17-methyltransferase 
Protein Synonyms/Alias
  
Gene Name
 TTHB056 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Thermus thermophilus (strain HB8 / ATCC 27634 / DSM 579) 
NCBI Taxa ID
 300852 
Lysine Modification
Position
Peptide
Type
References
264TPRGYALKYDLDTKEacetylation[1]
Reference
 [1] Acetylome with structural mapping reveals the significance of lysine acetylation in Thermus thermophilus.
 Okanishi H, Kim K, Masui R, Kuramitsu S.
 J Proteome Res. 2013 Aug 1;. [PMID: 23901841
Functional Description
  
Sequence Annotation
 REGION 82 87 S-adenosyl-L-homocysteine binding.
 REGION 132 133 S-adenosyl-L-homocysteine binding.
 REGION 237 240 S-adenosyl-L-homocysteine binding.
 BINDING 11 11 S-adenosyl-L-homocysteine; via carbonyl
 BINDING 182 182 S-adenosyl-L-homocysteine.
 BINDING 215 215 S-adenosyl-L-homocysteine; via amide  
Keyword
 3D-structure; Complete proteome; Methyltransferase; Plasmid; Reference proteome; Transferase. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 295 AA 
Protein Sequence
MGELFLVGMG PGDLPGLTQR AREALEGAEV VIGYSTYVKL LEEMGLLAGK EVVRKGMTEE 60
LDRAEEALER ALSGQRVALV SGGDPGIYGM AAPVLELMEE RGLKRVDGGV GLPGRFAGEE 120
GEVFLAVIPG VTAANAVASL LGSPLAHDTC LISLSDLLTP WPLIERRLHA AGQGDFVVVL 180
YNPQSKRRDW QLRKSAEILL EYRPKETPAA LVKSAYRKRQ EVALTTLEGL REAEAGMLTT 240
VVIGNRQSRF YEGTFLTPRG YALKYDLDTK EALPGETPGL SLVSPEGASS GRRDA 295 
Gene Ontology
 GO:0008168; F:methyltransferase activity; IEA:UniProtKB-KW.
 GO:0009236; P:cobalamin biosynthetic process; IEA:InterPro. 
Interpro
 IPR000878; 4pyrrol_Mease.
 IPR014777; 4pyrrole_Mease_sub1.
 IPR014776; 4pyrrole_Mease_sub2.
 IPR006363; Cbl_synth_CobJ/CibH_core. 
Pfam
 PF00590; TP_methylase 
SMART
  
PROSITE
  
PRINTS