CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-001341
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Putative phosphofructokinase PfkB 
Protein Synonyms/Alias
  
Gene Name
 pfkB 
Gene Synonyms/Alias
 Rv2029c; MT2088 
Created Date
 July 27, 2013 
Organism
 Mycobacterium tuberculosis 
NCBI Taxa ID
 1773 
Lysine Modification
Position
Peptide
Type
References
283SRGWSLIKSVRLGNApupylation[1]
Reference
 [1] Prokaryotic ubiquitin-like protein (Pup) proteome of Mycobacterium tuberculosis [corrected] .
 Festa RA, McAllister F, Pearce MJ, Mintseris J, Burns KE, Gygi SP, Darwin KH.
 PLoS One. 2010 Jan 6;5(1):e8589. [PMID: 20066036
Functional Description
  
Sequence Annotation
 ACT_SITE 265 265 By similarity.
 CROSSLNK 283 283 Isoglutamyl lysine isopeptide (Lys-Gln)  
Keyword
 Complete proteome; Isopeptide bond; Kinase; Reference proteome; Transferase; Ubl conjugation. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 339 AA 
Protein Sequence
MTEPAAWDEG KPRIITLTMN PALDITTSVD VVRPTEKMRC GAPRYDPGGG GINVARIVHV 60
LGGCSTALFP AGGSTGSLLM ALLGDAGVPF RVIPIAASTR ESFTVNESRT AKQYRFVLPG 120
PSLTVAEQEQ CLDELRGAAA SAAFVVASGS LPPGVAADYY QRVADICRRS STPLILDTSG 180
GGLQHISSGV FLLKASVREL RECVGSELLT EPEQLAAAHE LIDRGRAEVV VVSLGSQGAL 240
LATRHASHRF SSIPMTAVSG VGAGDAMVAA ITVGLSRGWS LIKSVRLGNA AGAAMLLTPG 300
TAACNRDDVE RFFELAAEPT EVGQDQYVWH PIVNPEASP 339 
Gene Ontology
 GO:0016301; F:kinase activity; IEA:UniProtKB-KW.
 GO:0016773; F:phosphotransferase activity, alcohol group as acceptor; IEA:InterPro.
 GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. 
Interpro
 IPR002173; Carboh/pur_kinase_PfkB_CS.
 IPR011611; PfkB_dom.
 IPR017583; Tagatose/fructose_Pkinase. 
Pfam
 PF00294; PfkB 
SMART
  
PROSITE
 PS00583; PFKB_KINASES_1
 PS00584; PFKB_KINASES_2 
PRINTS