CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-037398
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
  
Protein Name
 Protein kinase C-binding protein NELL1 
Protein Synonyms/Alias
  
Gene Name
 NRP1 
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
744RVKLRYQKPEEYDQLubiquitination[1]
764GHQGDHWKEGRVLLHubiquitination[1]
896GVKLKKDKLNTQSTYubiquitination[1, 2]
Reference
 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [2] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983] 
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 906 AA 
Protein Sequence
MERGLPLLCA VLALVLAPAG AFRNDKCGDT IKIESPGYLT SPGYPHSYHP SEKCEWLIQA 60
PDPYQRIMIN FNPHFDLEDR DCKYDYVEVF DGENENGHFR GKFCGKIAPP PVVSSGPFLF 120
IKFVSDYETH GAGFSIRYEI FKRGPECSQN YTTPSGVIKS PGFPEKYPNS LECTYIVFVP 180
KMSEIILEFE SFDLEPDSNP PGGMFCRYDR LEIWDGFPDV GPHIGRYCGQ KTPGRIRSSS 240
GILSMVFYTD SAIAKEGFSA NYSVLQSSVS EDFKCMEALG MESGEIHSDQ ITASSQYSTN 300
WSAERSRLNY PENGWTPGED SYREWIQVDL GLLRFVTAVG TQGAISKETK KKYYVKTYKI 360
DVSSNGEDWI TIKEGNKPVL FQGNTNPTDV VVAVFPKPLI TRFVRIKPAT WETGISMRFE 420
VYGCKITDYP CSGMLGMVSG LISDSQITSS NQGDRNWMPE NIRLVTSRSG WALPPAPHSY 480
INEWLQIDLG EEKIVRGIII QGGKHRENKV FMRKFKIGYS NNGSDWKMIM DDSKRKAKSF 540
EGNNNYDTPE LRTFPALSTR FIRIYPERAT HGGLGLRMEL LGCEVEAPTA GPTTPNGNLV 600
DECDDDQANC HSGTGDDFQL TGGTTVLATE KPTVIDSTIQ SEFPTYGFNC EFGWGSHKTF 660
CHWEHDNHVQ LKWSVLTSKT GPIQDHTGDG NFIYSQADEN QKGKVARLVS PVVYSQNSAH 720
CMTFWYHMSG SHVGTLRVKL RYQKPEEYDQ LVWMAIGHQG DHWKEGRVLL HKSLKLYQVI 780
FEGEIGKGNL GGIAVDDISI NNHISQEDCA RSTPGYEGEG EGDKNISRKP GNVLKTLDPI 840
LITIIAMSAL GVLLGAVCGV VLYCACWHNG MSERNLSALE NYNFELVDGV KLKKDKLNTQ 900
STYSEA 906 
Gene Ontology
 GO:0016020; C:membrane; IEA:InterPro.
 GO:0017154; F:semaphorin receptor activity; IEA:InterPro.
 GO:0005021; F:vascular endothelial growth factor-activated receptor activity; IEA:InterPro.
 GO:0001525; P:angiogenesis; IEA:InterPro.
 GO:0007411; P:axon guidance; IEA:InterPro.
 GO:0007155; P:cell adhesion; IEA:InterPro.
 GO:0035767; P:endothelial cell chemotaxis; IEA:InterPro.
 GO:0009887; P:organ morphogenesis; IEA:InterPro.
 GO:0048010; P:vascular endothelial growth factor receptor signaling pathway; IEA:InterPro. 
Interpro
 IPR000421; Coagulation_fac_5/8-C_type_dom.
 IPR008985; ConA-like_lec_gl_sf.
 IPR000859; CUB_dom.
 IPR008979; Galactose-bd-like.
 IPR000998; MAM_dom.
 IPR014648; Neuropilin.
 IPR022579; Neuropilin1_C.
 IPR027146; NRP1. 
Pfam
 PF00431; CUB
 PF11980; DUF3481
 PF00754; F5_F8_type_C
 PF00629; MAM 
SMART
 SM00042; CUB
 SM00231; FA58C
 SM00137; MAM 
PROSITE
 PS01180; CUB
 PS01285; FA58C_1
 PS01286; FA58C_2
 PS50022; FA58C_3
 PS00740; MAM_1
 PS50060; MAM_2 
PRINTS
 PR00020; MAMDOMAIN.