CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-025673
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 SAR1a gene homolog 2 variant 
Protein Synonyms/Alias
  
Gene Name
  
Gene Synonyms/Alias
  
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
46TTLLHMLKDDRLGQHubiquitination[1]
Reference
 [1] Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass.
 Povlsen LK, Beli P, Wagner SA, Poulsen SL, Sylvestersen KB, Poulsen JW, Nielsen ML, Bekker-Jensen S, Mailand N, Choudhary C.
 Nat Cell Biol. 2012 Oct;14(10):1089-98. [PMID: 23000965
Functional Description
  
Sequence Annotation
  
Keyword
 Endoplasmic reticulum; ER-Golgi transport; Golgi apparatus; GTP-binding; Nucleotide-binding; Protein transport; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 198 AA 
Protein Sequence
MSFIFDWIYS GFSSVLQFLG LYKKTGKLVF LGLDNAGKTT LLHMLKDDRL GQHVPTLHPT 60
SEELTIAGMT FTTFDLGGHV QARRVWKNYL PAINGIVFLV DCADHERLLE SKEELDSLMT 120
DETIANVPIL ILGNKIDRPE AISEERLREM FGLYGQTTGK GSLSLKELNA RPLEVFMCSV 180
LKRQGYGEGF RWMAQYID 198 
Gene Ontology
 GO:0005783; C:endoplasmic reticulum; IEA:UniProtKB-KW.
 GO:0005794; C:Golgi apparatus; IEA:UniProtKB-KW.
 GO:0005525; F:GTP binding; IEA:UniProtKB-KW.
 GO:0006886; P:intracellular protein transport; IEA:InterPro.
 GO:0016192; P:vesicle-mediated transport; IEA:UniProtKB-KW. 
Interpro
 IPR027417; P-loop_NTPase.
 IPR005225; Small_GTP-bd_dom.
 IPR006689; Small_GTPase_ARF/SAR.
 IPR006687; Small_GTPase_SAR1. 
Pfam
 PF00025; Arf 
SMART
 SM00178; SAR 
PROSITE
 PS51422; SAR1 
PRINTS
 PR00328; SAR1GTPBP.