| Tag | Content |
|---|
| CPLM ID | CPLM-000890 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Brain-specific angiogenesis inhibitor 2 |
Protein Synonyms/Alias | |
Gene Name | BAI2 |
Gene Synonyms/Alias | |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 556 | AGEIIYNKCPPNASG | ubiquitination | [1] |
|
Reference | [1] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments. Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA. Mol Cell Proteomics. 2013 Mar;12(3):825-31. [ PMID: 23266961] |
Functional Description | Might be involved in angiogenesis inhibition. |
Sequence Annotation | DOMAIN 309 362 TSP type-1 1.
DOMAIN 364 417 TSP type-1 2.
DOMAIN 419 472 TSP type-1 3.
DOMAIN 475 528 TSP type-1 4.
DOMAIN 871 923 GPS.
MOD_RES 1351 1351 Phosphotyrosine (By similarity).
CARBOHYD 106 106 N-linked (GlcNAc...) (Potential).
CARBOHYD 191 191 N-linked (GlcNAc...) (Potential).
CARBOHYD 192 192 N-linked (GlcNAc...) (Potential).
CARBOHYD 356 356 N-linked (GlcNAc...) (Potential).
CARBOHYD 437 437 N-linked (GlcNAc...) (Potential).
CARBOHYD 560 560 N-linked (GlcNAc...) (Potential).
CARBOHYD 645 645 N-linked (GlcNAc...) (Potential).
CARBOHYD 867 867 N-linked (GlcNAc...) (Potential).
DISULFID 321 355 By similarity.
DISULFID 325 361 By similarity.
DISULFID 336 345 By similarity.
DISULFID 376 411 By similarity.
DISULFID 380 416 By similarity.
DISULFID 391 401 By similarity.
DISULFID 431 466 By similarity.
DISULFID 435 471 By similarity.
DISULFID 446 456 By similarity.
DISULFID 487 522 By similarity.
DISULFID 491 527 By similarity.
DISULFID 502 512 By similarity.
DISULFID 534 569 By similarity.
DISULFID 557 587 By similarity.
DISULFID 874 906 By similarity.
DISULFID 894 908 By similarity. |
Keyword | Alternative splicing; Cell membrane; Complete proteome; Disulfide bond; G-protein coupled receptor; Glycoprotein; Membrane; Phosphoprotein; Receptor; Reference proteome; Repeat; Signal; Transducer; Transmembrane; Transmembrane helix. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 1585 AA |
Protein Sequence | MENTGWMGKG HRMTPACPLL LSVILSLRLA TAFDPAPSAC SALASGVLYG AFSLQDLFPT 60
IASGCSWTLE NPDPTKYSLY LRFNRQEQVC AHFAPRLLPL DHYLVNFTCL RPSPEEAVAQ 120
AESEVGRPEE EEAEAAAGLE LCSGSGPFTF LHFDKNFVQL CLSAEPSEAP RLLAPAALAF 180
RFVEVLLINN NNSSQFTCGV LCRWSEECGR AAGRACGFAQ PGCSCPGEAG AGSTTTTSPG 240
PPAAHTLSNA LVPGGPAPPA EADLHSGSSN DLFTTEMRYG EEPEEEPKVK TQWPRSADEP 300
GLYMAQTGDP AAEEWSPWSV CSLTCGQGLQ VRTRSCVSSP YGTLCSGPLR ETRPCNNSAT 360
CPVHGVWEEW GSWSLCSRSC GRGSRSRMRT CVPPQHGGKA CEGPELQTKL CSMAACPVEG 420
QWLEWGPWGP CSTSCANGTQ QRSRKCSVAG PAWATCTGAL TDTRECSNLE CPATDSKWGP 480
WNAWSLCSKT CDTGWQRRFR MCQATGTQGY PCEGTGEEVK PCSEKRCPAF HEMCRDEYVM 540
LMTWKKAAAG EIIYNKCPPN ASGSASRRCL LSAQGVAYWG LPSFARCISH EYRYLYLSLR 600
EHLAKGQRML AGEGMSQVVR SLQELLARRT YYSGDLLFSV DILRNVTDTF KRATYVPSAD 660
DVQRFFQVVS FMVDAENKEK WDDAQQVSPG SVHLLRVVED FIHLVGDALK AFQSSLIVTD 720
NLVISIQREP VSAVSSDITF PMRGRRGMKD WVRHSEDRLF LPKEVLSLSS PGKPATSGAA 780
GSPGRGRGPG TVPPGPGHSH QRLLPADPDE SSYFVIGAVL YRTLGLILPP PRPPLAVTSR 840
VMTVTVRPPT QPPAEPLITV ELSYIINGTT DPHCASWDYS RADASSGDWD TENCQTLETQ 900
AAHTRCQCQH LSTFAVLAQP PKDLTLELAG SPSVPLVIGC AVSCMALLTL LAIYAAFWRF 960
IKSERSIILL NFCLSILASN ILILVGQSRV LSKGVCTMTA AFLHFFFLSS FCWVLTEAWQ 1020
SYLAVIGRMR TRLVRKRFLC LGWGLPALVV AVSVGFTRTK GYGTSSYCWL SLEGGLLYAF 1080
VGPAAVIVLV NMLIGIIVFN KLMARDGISD KSKKQRAGSE RCPWASLLLP CSACGAVPSP 1140
LLSSASARNA MASLWSSCVV LPLLALTWMS AVLAMTDRRS VLFQALFAVF NSAQGFVITA 1200
VHCFLRREVQ DVVKCQMGVC RADESEDSPD SCKNGQLQIL SDFEKDVDLA CQTVLFKEVN 1260
TCNPSTITGT LSRLSLDEDE EPKSCLVGPE GSLSFSPLPG NILVPMAASP GLGEPPPPQE 1320
ANPVYMCGEG GLRQLDLTWL RPTEPGSEGD YMVLPRRTLS LQPGGGGGGG EDAPRARPEG 1380
TPRRAAKTVA HTEGYPSFLS VDHSGLGLGP AYGSLQNPYG MTFQPPPPTP SARQVPEPGE 1440
RSRTMPRTVP GSTMKMGSLE RKKLRYSDLD FEKVMHTRKR HSELYHELNQ KFHTFDRYRS 1500
QSTAKREKRW SVSSGGAAER SVCTDKPSPG ERPSLSQHRR HQSWSTFKSM TLGSLPPKPR 1560
ERLTLHRAAA WEPTEPPDGD FQTEV 1585 |
Gene Ontology | GO:0016021; C:integral to membrane; TAS:GDB. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0004930; F:G-protein coupled receptor activity; TAS:GDB. GO:0016525; P:negative regulation of angiogenesis; IEA:InterPro. GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro. GO:0007422; P:peripheral nervous system development; IEA:Compara. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |