CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-018295
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Solute carrier family 35 member F5 
Protein Synonyms/Alias
 Hepatitis C virus NS5A-transactivated protein 3; HCV NS5A-transactivated protein 3 
Gene Name
 SLC35F5 
Gene Synonyms/Alias
 NS5ATP3; UNQ2545/PRO6097 
Created Date
 July 27, 2013 
Organism
 Homo sapiens (Human) 
NCBI Taxa ID
 9606 
Lysine Modification
Position
Peptide
Type
References
177FHDLPSEKPESTNIDubiquitination[1]
187STNIDTEKTPKKSRVubiquitination[1]
214SSHALEAKLSRMSYPubiquitination[1, 2]
223SRMSYPVKEQESILKubiquitination[2]
230KEQESILKTVGKLTAubiquitination[1, 2]
Reference
 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 
Functional Description
 Putative solute transporter (Potential). 
Sequence Annotation
 DOMAIN 252 316 EamA.  
Keyword
 Alternative splicing; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 523 AA 
Protein Sequence
MVPPRRHRGA GRPGVLSSSP PFRLRSAKFS GIALEDLRRA LKTRLQMVCV FVMNRMNSQN 60
SGFTQRRRMA LGIVILLLVD VIWVASSELT SYVFTQYNKP FFSTFAKTSM FVLYLLGFII 120
WKPWRQQCTR GLRGKHAAFF ADAEGYFAAC TTDTTMNSSL SEPLYVPVKF HDLPSEKPES 180
TNIDTEKTPK KSRVRFSNIM EIRQLPSSHA LEAKLSRMSY PVKEQESILK TVGKLTATQV 240
AKISFFFCFV WFLANLSYQE ALSDTQVAIV NILSSTSGLF TLILAAVFPS NSGDRFTLSK 300
LLAVILSIGG VVLVNLAGSE KPAGRDTVGS IWSLAGAMLY AVYIVMIKRK VDREDKLDIP 360
MFFGFVGLFN LLLLWPGFFL LHYTGFEDFE FPNKVVLMCI IINGLIGTVL SEFLWLWGCF 420
LTSSLIGTLA LSLTIPLSII ADMCMQKVQF SWLFFAGAIP VFFSFFIVTL LCHYNNWDPV 480
MVGIRRIFAF ICRKHRIQRV PEDSEQCESL ISMHSVSQED GAS 523 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0006810; P:transport; IEA:UniProtKB-KW. 
Interpro
 IPR000620; DMT. 
Pfam
 PF00892; EamA 
SMART
  
PROSITE
  
PRINTS