UniProt Accession

 FRMSR_YEAST; P36088; D6VXL7 

Genbank Protein ID

 X75780; Z28069; BK006944 

Genbank Nucleotide ID

 CAA53405.1; CAA81906.1; DAA09087.1 

Protein Name

 Free methionine-R-sulfoxide reductase 

Protein Synonyms/Alias

 fRMsr; GAF domain-containing protein YKL069W 

Gene Name

 YKL069W; YKL340 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 

NCBI Taxa ID

 559292 

Lysine Modification

Position	Peptide	Type	References
98	CQMIQFGKGVCGTAA	ubiquitination	[1]
175	KLAKLINKSCVFK**	ubiquitination	[1]

Reference

 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301] 

Functional Description

 Catalyzes the reversible oxidation-reduction of the R- enantiomer of free methionine sulfoxide to methionine. Does not act on S-enantiomer of free methionine sulfoxide or R-enantiomer of dabsylated methionine sulfoxide. Involved in protection against oxidative stress. 

Sequence Annotation

 DOMAIN 99 177 GAF.  

Keyword

 3D-structure; Complete proteome; Cytoplasm; Nucleus; Oxidoreductase; Reference proteome; Stress response. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 180 AA 

Protein Sequence

Gene Ontology

 GO:0005737; C:cytoplasm; IDA:SGD.
 GO:0005634; C:nucleus; IDA:SGD.
 GO:0033745; F:L-methionine-(R)-S-oxide reductase activity; IEA:EC.
 GO:0070191; F:methionine-R-sulfoxide reductase activity; IDA:SGD.
 GO:0034599; P:cellular response to oxidative stress; IMP:SGD. 

Interpro

 IPR003018; GAF.
 IPR000614; UPF0067_CS. 

Pfam

 PF13185; GAF_2 

SMART

 SM00065; GAF 

PROSITE

 PS01320; UPF0067 

PRINTS