CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-003753
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 60S ribosomal protein L19-A 
Protein Synonyms/Alias
 L23; RP15L; RP33; YL14 
Gene Name
 RPL19A 
Gene Synonyms/Alias
 RPL23A; YL14A; YBR084C-A; YBR084BC 
Created Date
 July 27, 2013 
Organism
 Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) 
NCBI Taxa ID
 559292 
Lysine Modification
Position
Peptide
Type
References
19ASVVGVGKRKVWLDPubiquitination[1]
21VVGVGKRKVWLDPNEubiquitination[1]
46NAIRKLVKNGTIVKKubiquitination[1]
60KAVTVHSKSRTRAHAubiquitination[1]
117RDAGKIDKHLYHVLYacetylation[2]
117RDAGKIDKHLYHVLYubiquitination[1]
125HLYHVLYKESKGNAFacetylation[2]
125HLYHVLYKESKGNAFubiquitination[1]
146VEHIIQAKADAQREKubiquitination[1]
153KADAQREKALNEEAEacetylation[2]
153KADAQREKALNEEAEubiquitination[1]
186EKRDALLKEDA****ubiquitination[1]
Reference
 [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation.
 Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, VillĂ©n J.
 Nat Methods. 2013 Jul;10(7):676-82. [PMID: 23749301]
 [2] Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae.
 Henriksen P, Wagner SA, Weinert BT, Sharma S, Bacinskaja G, Rehman M, Juffer AH, Walther TC, Lisby M, Choudhary C.
 Mol Cell Proteomics. 2012 Nov;11(11):1510-22. [PMID: 22865919
Functional Description
  
Sequence Annotation
 MOD_RES 30 30 Phosphoserine.
 MOD_RES 37 37 Phosphoserine.
 MOD_RES 91 91 Phosphoserine.  
Keyword
 3D-structure; Complete proteome; Cytoplasm; Direct protein sequencing; Phosphoprotein; Reference proteome; Ribonucleoprotein; Ribosomal protein. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 189 AA 
Protein Sequence
MANLRTQKRL AASVVGVGKR KVWLDPNETS EIAQANSRNA IRKLVKNGTI VKKAVTVHSK 60
SRTRAHAQSK REGRHSGYGK RKGTREARLP SQVVWIRRLR VLRRLLAKYR DAGKIDKHLY 120
HVLYKESKGN AFKHKRALVE HIIQAKADAQ REKALNEEAE ARRLKNRAAR DRRAQRVAEK 180
RDALLKEDA 189 
Gene Ontology
 GO:0022625; C:cytosolic large ribosomal subunit; TAS:SGD.
 GO:0003735; F:structural constituent of ribosome; TAS:SGD.
 GO:0002181; P:cytoplasmic translation; TAS:SGD. 
Interpro
 IPR027547; Ribosomal_L19/L19e.
 IPR023638; Ribosomal_L19/L19e_CS.
 IPR000196; Ribosomal_L19/L19e_dom.
 IPR015972; Ribosomal_L19/L19e_dom1.
 IPR015974; Ribosomal_L19/L19e_dom3. 
Pfam
 PF01280; Ribosomal_L19e 
SMART
  
PROSITE
 PS00526; RIBOSOMAL_L19E 
PRINTS