CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-030277
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 TNFRSF1A-associated via death domain 
Protein Synonyms/Alias
  
Gene Name
 Tradd 
Gene Synonyms/Alias
 mCG_23521 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
143LNYILAQKPDRLRDEubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
  
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 310 AA 
Protein Sequence
MAAGQNGHEE WVGSAYLFLE SAVDKVILSE AYTDPKKKVA IYKALQTALS ESGDSSDVLQ 60
ILKIHCSDPQ LIVQLRFCGR VLCGRFLQAY REGALRTALQ RCMAPALAQE ALRLQLELRA 120
GAEQLDSWLT DEERCLNYIL AQKPDRLRDE ELAELEDELC KLTCDCTGQG GAIQVASAGS 180
KFPVSSPTEE KPLPAACQTF LFHGQLVVNR PLTLQDQQTF ARSVGLKWRR VGRSLQRNCR 240
ALRDPALDSL AYEYERDGLY EQAFQLLRRF MQAEGRRATL QRLVEALEEN ELTSLAEDLL 300
GQAEPDGGLA 310 
Gene Ontology
 GO:0005737; C:cytoplasm; IEA:InterPro.
 GO:0043235; C:receptor complex; IEA:Compara.
 GO:0060090; F:binding, bridging; IEA:Compara.
 GO:0004871; F:signal transducer activity; IEA:InterPro.
 GO:0097191; P:extrinsic apoptotic signaling pathway; IEA:Compara.
 GO:0006917; P:induction of apoptosis; IEA:InterPro.
 GO:0043123; P:positive regulation of I-kappaB kinase/NF-kappaB cascade; IEA:InterPro. 
Interpro
 IPR011029; DEATH-like_dom.
 IPR000488; Death_domain.
 IPR009095; TRADD_N. 
Pfam
 PF00531; Death
 PF09034; TRADD_N 
SMART
 SM00005; DEATH 
PROSITE
 PS50017; DEATH_DOMAIN 
PRINTS