| Tag | Content |
|---|
| CPLM ID | CPLM-008597 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Vitamin B6 transporter TPN1 |
Protein Synonyms/Alias | Transport of pyridoxine protein 1 |
Gene Name | TPN1 |
Gene Synonyms/Alias | YGL186C; G1370 |
Created Date | July 27, 2013 |
Organism | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) |
NCBI Taxa ID | 559292 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 477 | PELVGSSKEVEKDAV | ubiquitination | [1] | | 481 | GSSKEVEKDAVTNIH | ubiquitination | [1] |
|
Reference | [1] Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Swaney DL, Beltrao P, Starita L, Guo A, Rush J, Fields S, Krogan NJ, Villén J. Nat Methods. 2013 Jul;10(7):676-82. [ PMID: 23749301] |
Functional Description | Thiamine-regulated, high affinity import carrier of pyridoxine, pyridoxal and pyridoxamine. |
Sequence Annotation | |
Keyword | Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix; Transport. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 579 AA |
Protein Sequence | MNRDNMDTTK RKEDHTKHTT DVIEFYEEGT AASSLNIATE KANSSPSILR RIINRAAWLS 60
KKVDAMGVES TGIQRISPYE RGTSKKQFLH VAGLWLSATG GLSSMSSFLL GPLLFGLSFR 120
ESVASSLISV TIGCLIAAYC SIMGPQSGCR QMVTARYLFG WWFVKLVALA SIIGVMGWSV 180
VNSVVGGEML AAISNDKVPL WVGIVIVTVC SFLVAIFGIK QVIKVETYLS VPVLTAFLLL 240
YISSSDKYSF VNAYVSKGNL DSSTRKGNWM SFFSLCYSIT ATWGSITADY YILFPEDTPY 300
IQIFCLTFFG TFLPTCFVGI LGLLLASVAM SYKPWSVEYD SHGMGGLLWA GFQRWNGFGK 360
FCVVVLVFSL VSNNIINTYS AAFSIQLSSV FCAKIPRWFW SIVCTIICLV CALIGRNHFS 420
TILGNFLPMI GYWISMYFIL LFEENLVFRR FFLHLYTKEF PTVTGEINGP ELVGSSKEVE 480
KDAVTNIHLL KRKHKVTKHR YNWDKWEDYE VLTHGYAATF AFIVGVAGVV VGMAQAYWIG 540
PIAAKFGEYG GDVAMWLSMA FSGVVYPPCR YLELRKFGR 579 |
Gene Ontology | GO:0016021; C:integral to membrane; ISM:SGD. GO:0005886; C:plasma membrane; IDA:SGD. GO:0015205; F:nucleobase transmembrane transporter activity; IEA:InterPro. GO:0051183; F:vitamin transporter activity; IDA:SGD. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |