| Tag | Content |
|---|
| CPLM ID | CPLM-013724 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Zinc metalloprotease RasP |
Protein Synonyms/Alias | Regulating alternative sigma factor protease; Regulating anti-sigma-W factor activity protease |
Gene Name | rasP |
Gene Synonyms/Alias | GK1256 |
Created Date | July 27, 2013 |
Organism | Geobacillus kaustophilus (strain HTA426) |
NCBI Taxa ID | 235909 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 392 | GKPVDRQKEGMVHFI | acetylation | [1] |
|
Reference | [1] Proteomic analysis of acetylation in thermophilic Geobacillus kaustophilus. Lee DW, Kim D, Lee YJ, Kim JA, Choi JY, Kang S, Pan JG. Proteomics. 2013 Aug;13(15):2278-82. [ PMID: 23696451] |
Functional Description | Is responsible for Site-2 cleavage of the RsiW anti- sigma factor. This results, after a third proteolytic step catalyzed by the ClpXP protease, in the release of SigW and the transcription activation of the genes under the control of the sigma-W factor (By similarity). |
Sequence Annotation | DOMAIN 186 271 PDZ.
ACT_SITE 23 23 Potential.
METAL 22 22 Zinc; catalytic (Potential).
METAL 26 26 Zinc; catalytic (Potential). |
Keyword | Cell membrane; Complete proteome; Hydrolase; Membrane; Metal-binding; Metalloprotease; Protease; Transmembrane; Transmembrane helix; Zinc. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 421 AA |
Protein Sequence | MVETLESIIS FIVVFGALVF FHELGHLLLA KRAGILCREF AIGFGPKVFS FKKNETVYTI 60
RLLPLGGFVR MAGEDPETIE LKRGQVVGLL LDESGQVEKI VLNHKDDYPN IRVVEVEEAD 120
LEHGMYVTGY TDGERFERFT VKEPAFFVVD RQEIQIAPYH RQFAAKTLGQ RTMTILAGPL 180
ANFLLSLVVF IIIGLLQGYP VDKPVIGELT PEGAARAAGL KQGDKVIAIN GERMETWTEI 240
VNTIRAHPGE PLQFQIERNG KERSVTVTPE AKTVQGETIG LIGVYQPMEK SVLGSIKQGL 300
VETYYWTREI VTGLGQLITG QFQLDMLSGP VGIAVSTGKV AESGIYYLMK WGAILSINLG 360
IVNLLPLPAL DGGRLLFFAI EAVRGKPVDR QKEGMVHFIG FALLMLLMLV VTWNDIQKFF 420
L 421 |
Gene Ontology | GO:0016021; C:integral to membrane; IEA:UniProtKB-KW. GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell. GO:0046872; F:metal ion binding; IEA:UniProtKB-KW. GO:0004222; F:metalloendopeptidase activity; IEA:InterPro. GO:0006508; P:proteolysis; IEA:UniProtKB-KW. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |