UniProt Accession

 B4DLR8_HUMAN; B4DLR8 

Genbank Protein ID

 AC092115; AK297125 

Genbank Nucleotide ID

 BAG59630.1 

Protein Name

 NAD(P)H dehydrogenase [quinone] 1 

Protein Synonyms/Alias

 cDNA FLJ50573, highly similar to Homo sapiens NAD(P)H dehydrogenase, quinone 1 (NQO1), transcript variant 3, mRNA 

Gene Name

 NQO1 

Gene Synonyms/Alias

  

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
23	TSFNYAMKEAAAAAL	ubiquitination	[1, 2]
31	EAAAAALKKKGWEVV	ubiquitination	[1, 2]
32	AAAAALKKKGWEVVE	ubiquitination	[3]
33	AAAALKKKGWEVVES	ubiquitination	[1, 2, 3]
54	FNPIISRKDITGKLK	ubiquitination	[1, 2]
59	SRKDITGKLKDPANF	ubiquitination	[1, 2, 3]
61	KDITGKLKDPANFQY	ubiquitination	[1, 2, 3, 4]
77	AESVLAYKEGHLSPD	ubiquitination	[1, 2, 3]
90	PDIVAEQKKLEAADL	ubiquitination	[1, 2]
137	IQILEGWKKRLENIW	ubiquitination	[1, 2, 3, 4]
138	QILEGWKKRLENIWD	ubiquitination	[4]
169	QAGFLMKKEVQDEEK	ubiquitination	[1]
176	KEVQDEEKNKKFGLS	ubiquitination	[1]
179	QDEEKNKKFGLSVGH	ubiquitination	[1, 2, 3]
190	SVGHHLGKSIPTDNQ	ubiquitination	[1, 2, 3]
199	IPTDNQIKARK****	ubiquitination	[1, 2]
202	DNQIKARK*******	ubiquitination	[2]

Reference

 [1] Systematic and quantitative assessment of the ubiquitin-modified proteome.
 Kim W, Bennett EJ, Huttlin EL, Guo A, Li J, Possemato A, Sowa ME, Rad R, Rush J, Comb MJ, Harper JW, Gygi SP.
 Mol Cell. 2011 Oct 21;44(2):325-40. [PMID: 21906983]
 [2] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661]
 [3] Global identification of modular cullin-RING ligase substrates.
 Emanuele MJ, Elia AE, Xu Q, Thoma CR, Izhar L, Leng Y, Guo A, Chen YN, Rush J, Hsu PW, Yen HC, Elledge SJ.
 Cell. 2011 Oct 14;147(2):459-74. [PMID: 21963094]
 [4] Refined preparation and use of anti-diglycine remnant (K-ε-GG) antibody enables routine quantification of 10,000s of ubiquitination sites in single proteomics experiments.
 Udeshi ND, Svinkina T, Mertins P, Kuhn E, Mani DR, Qiao JW, Carr SA.
 Mol Cell Proteomics. 2013 Mar;12(3):825-31. [PMID: 23266961] 

Functional Description

  

Sequence Annotation

  

Keyword

 Complete proteome; Reference proteome. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 202 AA 

Protein Sequence

Gene Ontology

  

Interpro

 IPR003680; Flavodoxin_fold. 

Pfam

 PF02525; Flavodoxin_2 

SMART

  

PROSITE

  

PRINTS