UniProt Accession

 GALA_HUMAN; P22466; Q14413 

Genbank Protein ID

 L11144; M77140; BC030241 

Genbank Nucleotide ID

 AAA18248.1; AAA60178.1; AAH30241.1 

Protein Name

 Galanin peptides 

Protein Synonyms/Alias

 Galanin; Galanin message-associated peptide; GMAP 

Gene Name

 GAL 

Gene Synonyms/Alias

 GAL1; GALN; GLNN 

Created Date

 July 27, 2013 

Organism

 Homo sapiens (Human) 

NCBI Taxa ID

 9606 

Lysine Modification

Position	Peptide	Type	References
57	NHRSFSDKNGLTSKR	ubiquitination	[1]
73	LRPEDDMKPGSFDRS	ubiquitination	[1]

Reference

 [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization.
 Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW.
 Nature. 2013 Apr 18;496(7445):372-6. [PMID: 23503661] 

Functional Description

 Contracts smooth muscle of the gastrointestinal and genitourinary tract, regulates growth hormone release, modulates insulin release, and may be involved in the control of adrenal secretion. 

Sequence Annotation

 MOD_RES 117 117 Phosphoserine.  

Keyword

 Cleavage on pair of basic residues; Complete proteome; Direct protein sequencing; Hormone; Neuropeptide; Phosphoprotein; Polymorphism; Reference proteome; Secreted; Signal. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 123 AA 

Protein Sequence

Gene Ontology

 GO:0005576; C:extracellular region; TAS:Reactome.
 GO:0005794; C:Golgi apparatus; IEA:Compara.
 GO:0030141; C:secretory granule; IEA:Compara.
 GO:0005184; F:neuropeptide hormone activity; NAS:UniProtKB.
 GO:0007631; P:feeding behavior; IEA:Compara.
 GO:0030252; P:growth hormone secretion; NAS:UniProtKB.
 GO:0006954; P:inflammatory response; IEA:Compara.
 GO:0030073; P:insulin secretion; NAS:UniProtKB.
 GO:0050672; P:negative regulation of lymphocyte proliferation; IEA:Compara.
 GO:0007399; P:nervous system development; IEA:Compara.
 GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
 GO:0043065; P:positive regulation of apoptotic process; IEA:Compara.
 GO:0031943; P:regulation of glucocorticoid metabolic process; IEA:Compara.
 GO:0042493; P:response to drug; IEA:Compara.
 GO:0043627; P:response to estrogen stimulus; IEA:Compara.
 GO:0032868; P:response to insulin stimulus; IEA:Compara.
 GO:0006939; P:smooth muscle contraction; NAS:UniProtKB. 

Interpro

 IPR008174; Galanin.
 IPR008175; Galanin_pre.
 IPR013068; GMAP. 

Pfam

 PF01296; Galanin
 PF06540; GMAP 

SMART

 SM00071; Galanin 

PROSITE

 PS00861; GALANIN 

PRINTS

 PR00273; GALANIN.