| Tag | Content |
|---|
| CPLM ID | CPLM-016381 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Protein phosphatase 1 regulatory subunit 12B |
Protein Synonyms/Alias | Myosin phosphatase-targeting subunit 2; Myosin phosphatase target subunit 2 |
Gene Name | Ppp1r12b |
Gene Synonyms/Alias | Mypt2 |
Created Date | July 27, 2013 |
Organism | Mus musculus (Mouse) |
NCBI Taxa ID | 10090 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 961 | KSDNQRLKDENGALI | ubiquitination | [1] |
|
Reference | [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues. Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C. Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [ PMID: 22790023] |
Functional Description | Regulates myosin phosphatase activity. Augments Ca(2+) sensitivity of the contractile apparatus (By similarity). |
Sequence Annotation | REPEAT 57 86 ANK 1.
REPEAT 90 119 ANK 2.
REPEAT 123 152 ANK 3.
REPEAT 216 245 ANK 4.
REPEAT 249 278 ANK 5.
MOD_RES 502 502 Phosphoserine.
MOD_RES 833 833 Phosphoserine. |
Keyword | Alternative splicing; ANK repeat; Complete proteome; Cytoplasm; Phosphoprotein; Reference proteome; Repeat. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 976 AA |
Protein Sequence | MAELEHLGGK RAESARARRA EQLRRWRGSL TEQEPAERQG AGRQLQTRRG SPRVRFEDGA 60
VFLAACSSGD TDEVKKLLAR GADINTVNVD GLTALHQACI DENLDMVKFL VENRANVNQQ 120
DNEGWTPLHA AASCGYLNIA EYFISHGASV GIVNSEGEVP SDLAEEPAMK DLLLEQVKKQ 180
GVDLEQSRKE EEQQMLQDAR QWLNSGRIED VRQARSGATA LHVAAAKGYS EVLRLLIQAG 240
YELNVQDHDG WTPLHAAAHW GVKEACSILA EALCDMDIRN KLGQTPFDVA DEGLVEHLEM 300
LQKKQDVLRS EKETRNKLIE SDLNSKFQSG LFKNKEKMLY EEEIPKSQDT EEENKESSSS 360
SSEEEEGEDE VSESETEKEA DKKPEATVNH SNSEIKSRIM EQIPAPAQNT FSASSARRLS 420
SLFNKAEEPK DESPSSWRLG LRKTGSHNML SEVANSREAL RDRGSSIYRS SSSPRISALL 480
DDKDKERENK SYFSMLVPRR LSSTSDIEEK ENRESAVNLV RSGSHTRQLW RDEAKGSETP 540
QTIAPSTYTS TYLKRTPYKS QADSTAEKTA DSVSSSTPLC VITNRPAPST ANGVPAATVF 600
SSAGTDPSVE AREKRRSYLT PVRDEEAESL RKARSRQARQ TRRSTQGVTL TDLQEAEKTF 660
SRSRAERQAQ EQPGEKLEDP GGLEGSTKKQ EPSAAPTKGA GEGRSLEEEP IYHRLRYPTQ 720
PDKPTTPVSP SASRPSLYTG SHLLRTSRAS GPDSENSETS THATAAKEMD TSEKGEADLD 780
DQSSNRLSVR ERRRAKDRRR GTGINFWTND EDETDVSEEV KEALHERLSR LESGGTNPTS 840
SDSYSDRASA RARREAREAR LASLTSRVEE DSNRDYKKLY ESALTENQKL KTKLQEAQLE 900
LADIKAKLEK MAQQKQEKTS DRSSVLEVEK RERRALERKM SEMEEEMKVL TELKSDNQRL 960
KDENGALIRV ISKLSK 976 |
Gene Ontology | |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |