CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-028077
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 Ef1alpha-like factor, isoform A 
Protein Synonyms/Alias
 Ef1alpha-like factor, isoform B; RE07731p 
Gene Name
 Elf 
Gene Synonyms/Alias
 CG6382; Dmel_CG6382 
Created Date
 July 27, 2013 
Organism
 Drosophila melanogaster (Fruit fly) 
NCBI Taxa ID
 7227 
Lysine Modification
Position
Peptide
Type
References
329REHAMLAKTAGVKHLacetylation[1]
367DKILPYLKKLGFNPAacetylation[1]
368KILPYLKKLGFNPAKacetylation[1]
613NKTIAIGKVLKVVE*acetylation[1]
Reference
 [1] Proteome-wide mapping of the Drosophila acetylome demonstrates a high degree of conservation of lysine acetylation.
 Weinert BT, Wagner SA, Horn H, Henriksen P, Liu WR, Olsen JV, Jensen LJ, Choudhary C.
 Sci Signal. 2011 Jul 26;4(183):ra48. [PMID: 21791702
Functional Description
  
Sequence Annotation
  
Keyword
 Complete proteome; GTP-binding; Nucleotide-binding; Reference proteome. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 619 AA 
Protein Sequence
MAAQENTEIS TKFSTLNVNA VEFVPSFSYN SVVNVAEEAA AVVVAAAAAE ETADPGPASG 60
SATPATTPDS VGSGGSTAGA APPPPTAQGA GAAAPSAQPP TSSSNSASPA PGSPATTPSA 120
GAAAADPTPI DGLNPSDKIA NNETDPADSW DVDDAVITPE DEEVEDAEFT EGEATPKVSK 180
KKVVKVEENR SKREHVNVVF IGHVDAGKST IGGQIMSLTG MVDKRTLEKY EREAREKSRE 240
SWYLSWALDT NQEERDKGKT VEVGRAFFET DRKHFTILDA PGHKSFVPNM IGGAAQADLA 300
VLVISARKGE FETGFDRGGQ TREHAMLAKT AGVKHLVVLV NKMDDPTVNW DQTRYNECKD 360
KILPYLKKLG FNPAKDLTFM PCSGLSGYGL KDQIPETLCP WYRGPAFIPF IDELPSLNRK 420
SDGPFIMPIV DKYKDMGTVV MGKVESGTAR KGQNLLVMPN RTQVAVDQLF SDDFEVTSVG 480
PGENVKIKLK GIEEEDVSPG FVLCDAANPI KTGKIFDAQV VILEHKSIIC AGYSAVMHIH 540
CAAEEVTVKA LICLVDKKSG DKSKTRPRFV KQDQVAIMRI ECSGMICLEQ FKLFPQMGRF 600
TLRDENKTIA IGKVLKVVE 619 
Gene Ontology
 GO:0005829; C:cytosol; ISS:FlyBase.
 GO:0005525; F:GTP binding; ISS:FlyBase.
 GO:0003924; F:GTPase activity; NAS:FlyBase.
 GO:0003747; F:translation release factor activity; NAS:FlyBase. 
Interpro
 IPR009818; Ataxin-2_C.
 IPR000795; EF_GTP-bd_dom.
 IPR027417; P-loop_NTPase.
 IPR009001; Transl_elong_EF1A/Init_IF2_C.
 IPR004161; Transl_elong_EFTu/EF1A_2.
 IPR004160; Transl_elong_EFTu/EF1A_C.
 IPR009000; Transl_elong_init/rib_B-barrel. 
Pfam
 PF00009; GTP_EFTU
 PF03144; GTP_EFTU_D2
 PF03143; GTP_EFTU_D3
 PF07145; PAM2 
SMART
  
PROSITE
 PS00301; EFACTOR_GTP 
PRINTS
 PR00315; ELONGATNFCT.