Tag | Content |
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CPLM ID | CPLM-003370 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | HTH-type transcriptional regulator RpiR |
Protein Synonyms/Alias | Als operon repressor |
Gene Name | rpiR |
Gene Synonyms/Alias | alsR; yjcY; b4089; JW4050 |
Created Date | July 27, 2013 |
Organism | Escherichia coli (strain K12) |
NCBI Taxa ID | 83333 |
Lysine Modification | Position | Peptide | Type | References |
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69 | AMIVKVSKLLGFSGF | acetylation | [1] |
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Reference | [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli. Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C. Mol Cell. 2013 Jul 25;51(2):265-72. [ PMID: 23830618] |
Functional Description | Regulatory protein involved in rpiB gene repression. Also involved in als operon repression. |
Sequence Annotation | DOMAIN 14 90 HTH rpiR-type. DOMAIN 134 274 SIS. DNA_BIND 50 69 H-T-H motif (Potential). |
Keyword | Complete proteome; DNA-binding; Reference proteome; Repressor; Transcription; Transcription regulation. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 296 AA |
Protein Sequence | MSQSEFDSAL PNGIGLAPYL RMKQEGMTEN ESRIVEWLLK PGNLSCAPAI KDVAEALAVS 60 EAMIVKVSKL LGFSGFRNLR SALEDYFSQS EQVLPSELAF DEAPQDVVNK VFNITLRTIM 120 EGQSIVNVDE IHRAARFFYQ ARQRDLYGAG GSNAICADVQ HKFLRIGVRC QAYPDAHIMM 180 MSASLLQEGD VVLVVTHSGR TSDVKAAVEL AKKNGAKIIC ITHSYHSPIA KLADYIICSP 240 APETPLLGRN ASARILQLTL LDAFFVSVAQ LNIEQANINM QKTGAIVDFF SPGALK 296 |
Gene Ontology | GO:0030246; F:carbohydrate binding; IEA:InterPro. GO:0003677; F:DNA binding; IEA:UniProtKB-KW. GO:0003700; F:sequence-specific DNA binding transcription factor activity; IEA:InterPro. GO:0005975; P:carbohydrate metabolic process; IEA:InterPro. GO:0045892; P:negative regulation of transcription, DNA-dependent; IDA:EcoCyc. GO:0006351; P:transcription, DNA-dependent; IEA:UniProtKB-KW. |
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