UniProt Accession

 RS12_ECOLI; P0A7S3; P02367; Q2M707; Q9F5N3 

Genbank Protein ID

 V00355; U18997; U00096; AP009048; AF312716; AF312717; V00354; J01688 

Genbank Nucleotide ID

 CAA23648.1; AAA58139.1; AAC76367.1; BAE77949.1; AAG30936.1; AAG30937.1; CAA23647.1; AAA50988.1 

Protein Name

 30S ribosomal protein S12 

Protein Synonyms/Alias

  

Gene Name

 rpsL 

Gene Synonyms/Alias

 strA; b3342; JW3304 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
108	ALDCSGVKDRKQARS	acetylation	[1]

Reference

 [1] Lysine acetylation is a highly abundant and evolutionarily conserved modification in Escherichia coli.
 Zhang J, Sprung R, Pei J, Tan X, Kim S, Zhu H, Liu CF, Grishin NV, Zhao Y.
 Mol Cell Proteomics. 2009 Feb;8(2):215-25. [PMID: 18723842] 

Functional Description

 With S4 and S5 plays an important role in translational accuracy. 

Sequence Annotation

 MOD_RES 89 89 3-methylthioaspartic acid.
 MOD_RES 108 108 N6-acetyllysine.  

Keyword

 3D-structure; Acetylation; Antibiotic resistance; Complete proteome; Direct protein sequencing; Reference proteome; Ribonucleoprotein; Ribosomal protein; RNA-binding; rRNA-binding; tRNA-binding. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 124 AA 

Protein Sequence

Gene Ontology

 GO:0022627; C:cytosolic small ribosomal subunit; IDA:EcoCyc.
 GO:0034336; F:misfolded RNA binding; IDA:EcoCyc.
 GO:0019843; F:rRNA binding; IDA:EcoCyc.
 GO:0003735; F:structural constituent of ribosome; IEA:InterPro.
 GO:0000049; F:tRNA binding; IEA:HAMAP.
 GO:0000372; P:Group I intron splicing; IDA:EcoCyc.
 GO:0033120; P:positive regulation of RNA splicing; IDA:EcoCyc.
 GO:0046677; P:response to antibiotic; IEA:UniProtKB-KW.
 GO:0034337; P:RNA folding; IDA:EcoCyc.
 GO:0006412; P:translation; IMP:EcoCyc. 

Interpro

 IPR012340; NA-bd_OB-fold.
 IPR006032; Ribosomal_S12/S23.
 IPR005679; Ribosomal_S12_bac. 

Pfam

 PF00164; Ribosomal_S12 

SMART

  

PROSITE

 PS00055; RIBOSOMAL_S12 

PRINTS

 PR01034; RIBOSOMALS12.