UniProt Accession

 ACCD_ECOLI; P0A9Q5; P08193; P76937; P78251 

Genbank Protein ID

 M32445; J02808; M68934; U00096; AP009048; S53037 

Genbank Nucleotide ID

 AAA23807.1; AAA23801.1; AAA23965.1; AAC75376.1; BAA16173.1; AAB24894.2 

Protein Name

 Acetyl-coenzyme A carboxylase carboxyl transferase subunit beta 

Protein Synonyms/Alias

 ACCase subunit beta; Acetyl-CoA carboxylase carboxyltransferase subunit beta 

Gene Name

 accD 

Gene Synonyms/Alias

 dedB; usg; b2316; JW2313 

Created Date

 July 27, 2013 

Organism

 Escherichia coli (strain K12) 

NCBI Taxa ID

 83333 

Lysine Modification

Position	Peptide	Type	References
80	LGSELEPKDVLKFRD	acetylation	[1]
105	AQKETGEKDALVVMK	acetylation	[1]
179	MSLMQMAKTSAALAK	acetylation	[1]
186	KTSAALAKMQERGLP	acetylation	[1]
240	IEQTVREKLPPGFQR	acetylation	[1]
254	RSEFLIEKGAIDMIV	acetylation	[1]
269	RRPEMRLKLASILAK	acetylation	[1]

Reference

 [1] Acetyl-Phosphate Is a Critical Determinant of Lysine Acetylation in E. coli.
 Weinert BT, Iesmantavicius V, Wagner SA, Schölz C, Gummesson B, Beli P, Nyström T, Choudhary C.
 Mol Cell. 2013 Jul 25;51(2):265-72. [PMID: 23830618] 

Functional Description

 Component of the acetyl coenzyme A carboxylase (ACC) complex. Biotin carboxylase (BC) catalyzes the carboxylation of biotin on its carrier protein (BCCP) and then the CO(2) group is transferred by the transcarboxylase to acetyl-CoA to form malonyl- CoA. 

Sequence Annotation

 ZN_FING 27 49 C4-type (Probable).
 METAL 27 27 Zinc.
 METAL 30 30 Zinc.
 METAL 46 46 Zinc.
 METAL 49 49 Zinc.  

Keyword

 3D-structure; ATP-binding; Complete proteome; Cytoplasm; Fatty acid biosynthesis; Fatty acid metabolism; Ligase; Lipid biosynthesis; Lipid metabolism; Metal-binding; Nucleotide-binding; Reference proteome; RNA-binding; Translation regulation; Zinc; Zinc-finger. 

Sequence Source

 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 

Protein Length

 304 AA 

Protein Sequence

Gene Ontology

 GO:0009329; C:acetate CoA-transferase complex; IDA:EcoCyc.
 GO:0005829; C:cytosol; IDA:UniProtKB.
 GO:0003989; F:acetyl-CoA carboxylase activity; IDA:EcoliWiki.
 GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
 GO:0003677; F:DNA binding; IMP:EcoCyc.
 GO:0003729; F:mRNA binding; IDA:EcoCyc.
 GO:0008270; F:zinc ion binding; IDA:EcoCyc.
 GO:0042759; P:long-chain fatty acid biosynthetic process; NAS:EcoliWiki.
 GO:2001295; P:malonyl-CoA biosynthetic process; IEA:UniProtKB-UniPathway.
 GO:0017148; P:negative regulation of translation; IDA:EcoCyc. 

Interpro

 IPR000438; Acetyl_CoA_COase_Trfase_b_su.
 IPR000022; Carboxyl_trans.
 IPR011762; COA_CT_N. 

Pfam

 PF01039; Carboxyl_trans 

SMART

  

PROSITE

 PS50980; COA_CT_NTER 

PRINTS

 PR01070; ACCCTRFRASEB.