| Tag | Content |
|---|
| CPLM ID | CPLM-012316 |
UniProt Accession | |
Genbank Protein ID | |
Genbank Nucleotide ID | |
Protein Name | Caprin-1 |
Protein Synonyms/Alias | Cell cycle-associated protein 1; Cytoplasmic activation- and proliferation-associated protein 1; GPI-anchored membrane protein 1; GPI-anchored protein p137; GPI-p137; p137GPI; Membrane component chromosome 11 surface marker 1; RNA granule protein 105 |
Gene Name | CAPRIN1 |
Gene Synonyms/Alias | GPIAP1; GPIP137; M11S1; RNG105 |
Created Date | July 27, 2013 |
Organism | Homo sapiens (Human) |
NCBI Taxa ID | 9606 |
Lysine Modification | Position | Peptide | Type | References |
|---|
| 110 | TNNLEFAKELQRSFM | ubiquitination | [1] | | 125 | ALSQDIQKTIKKTAR | ubiquitination | [1] | | 158 | ELQYVLDKLGDDEVR | ubiquitination | [1] | | 169 | DEVRTDLKQGLNGVP | ubiquitination | [1] |
|
Reference | [1] Landscape of the PARKIN-dependent ubiquitylome in response to mitochondrial depolarization. Sarraf SA, Raman M, Guarani-Pereira V, Sowa ME, Huttlin EL, Gygi SP, Harper JW. Nature. 2013 Apr 18;496(7445):372-6. [ PMID: 23503661] |
Functional Description | May regulate the transport and translation of mRNAs of proteins involved in synaptic plasticity in neurons and cell proliferation and migration in multiple cell types (By similarity). |
Sequence Annotation | REGION 360 381 G3BP1-binding.
MOD_RES 2 2 N-acetylproline.
MOD_RES 10 10 Phosphoserine. |
Keyword | Acetylation; Alternative splicing; Cell projection; Coiled coil; Complete proteome; Cytoplasm; Differentiation; Direct protein sequencing; Glycoprotein; Phosphoprotein; Polymorphism; Protein synthesis inhibitor; Reference proteome; RNA-binding. |
Sequence Source | UniProt (SWISSPROT/TrEMBL); GenBank; EMBL |
Protein Length | 709 AA |
Protein Sequence | MPSATSHSGS GSKSSGPPPP SGSSGSEAAA GAGAAAPASQ HPATGTGAVQ TEAMKQILGV 60
IDKKLRNLEK KKGKLDDYQE RMNKGERLNQ DQLDAVSKYQ EVTNNLEFAK ELQRSFMALS 120
QDIQKTIKKT ARREQLMREE AEQKRLKTVL ELQYVLDKLG DDEVRTDLKQ GLNGVPILSE 180
EELSLLDEFY KLVDPERDMS LRLNEQYEHA SIHLWDLLEG KEKPVCGTTY KVLKEIVERV 240
FQSNYFDSTH NHQNGLCEEE EAASAPAVED QVPEAEPEPA EEYTEQSEVE STEYVNRQFM 300
AETQFTSGEK EQVDEWTVET VEVVNSLQQQ PQAASPSVPE PHSLTPVAQA DPLVRRQRVQ 360
DLMAQMQGPY NFIQDSMLDF ENQTLDPAIV SAQPMNPTQN MDMPQLVCPP VHSESRLAQP 420
NQVPVQPEAT QVPLVSSTSE GYTASQPLYQ PSHATEQRPQ KEPIDQIQAT ISLNTDQTTA 480
SSSLPAASQP QVFQAGTSKP LHSSGINVNA APFQSMQTVF NMNAPVPPVN EPETLKQQNQ 540
YQASYNQSFS SQPHQVEQTE LQQEQLQTVV GTYHGSPDQS HQVTGNHQQP PQQNTGFPRS 600
NQPYYNSRGV SRGGSRGARG LMNGYRGPAN GFRGGYDGYR PSFSNTPNSG YTQSQFSAPR 660
DYSGYQRDGY QQNFKRGSGQ SGPRGAPRGN ILWW 694 |
Gene Ontology | GO:0000932; C:cytoplasmic mRNA processing body; ISS:UniProtKB. GO:0010494; C:cytoplasmic stress granule; ISS:UniProtKB. GO:0005829; C:cytosol; IEA:UniProtKB-SubCell. GO:0030425; C:dendrite; IEA:UniProtKB-SubCell. GO:0005887; C:integral to plasma membrane; TAS:ProtInc. GO:0003723; F:RNA binding; ISS:UniProtKB. GO:0017148; P:negative regulation of translation; ISS:UniProtKB. GO:0050775; P:positive regulation of dendrite morphogenesis; ISS:UniProtKB. GO:0061003; P:positive regulation of dendritic spine morphogenesis; ISS:UniProtKB. |
Interpro | |
Pfam | |
SMART | |
PROSITE | |
PRINTS | |