CPLM 1.0 - Compendium of Protein Lysine Modification
TagContent
CPLM ID CPLM-041939
UniProt Accession
Genbank Protein ID
Genbank Nucleotide ID
Protein Name
 MCG115189 
Protein Synonyms/Alias
 Protein Gpr116 
Gene Name
 Gpr116 
Gene Synonyms/Alias
 mCG_115189 
Created Date
 July 27, 2013 
Organism
 Mus musculus (Mouse) 
NCBI Taxa ID
 10090 
Lysine Modification
Position
Peptide
Type
References
1294RWSSQHSKSTSIGSSubiquitination[1]
Reference
 [1] Proteomic analyses reveal divergent ubiquitylation site patterns in murine tissues.
 Wagner SA, Beli P, Weinert BT, Schölz C, Kelstrup CD, Young C, Nielsen ML, Olsen JV, Brakebusch C, Choudhary C.
 Mol Cell Proteomics. 2012 Dec;11(12):1578-85. [PMID: 22790023] 
Functional Description
  
Sequence Annotation
  
Keyword
 Cell membrane; Complete proteome; Membrane; Reference proteome; Transmembrane; Transmembrane helix. 
Sequence Source
 UniProt (SWISSPROT/TrEMBL); GenBank; EMBL 
Protein Length
 1348 AA 
Protein Sequence
MRSPRTFTFY FLLLVICSSE AALSTPTEPI VQPSILQEHE LAGEELLRPK RAAAAGDRVA 60
EEYMVDIEIS FENVSFLESI RAHLNNLSFP IRGTEADILN IAMTTVCTPA GNDLLCFCEK 120
GYQWSEERCL HSLTCQDYDS ALPGGYCSCL KGLPPQGPFC QLPEAFITLK LKVRLNIGFQ 180
EDLKNTSSAL YRSYKTDLER AFRAGYRTLP GFRSVTVTQF TKGSVVVNYV VRVTSAPLPG 240
SIHKANEQVI QNLNHTYKMD YNSFQGTPSN ETKFTVIPEF IFEGDNVTLE CETEFVTSNT 300
SWYYGEKRSD IQNSDKYSIH TTVINNISLI TRLTIYNFTQ HDAGMYGCNV TLDIFEYGTV 360
RKLDVTPIRI LAKEERKVVC DNHPISLNCC SENIANWSSI EWKQEGKISI LGNPESDLES 420
SCSTYTLKAD GTQCPSGSSG TTVIYTCEFV SAYGARGSKN IAVTFTSVAN LTITRDPISV 480
SEGQSFSITC LSDVSSFDEV YWNTSAGIKI HPRFYTMRRY QDGAESVLMV KTSTREWNGT 540
YHCIFRYKNS YSIATKDVTV HPLPLVSDIM MDPLEASGLC TSSHQFKCCV EEDAGEEYAV 600
TFHVDSSSFP AEREVIGKQA CYTYSLPANL PRCPKDIAVF CHFTNAANSS VRSPSMKLKL 660
IPRENVTCQD PIIGIGDPGK VIQKLCQFSG VYGSPGQAIG GTVTYKCVGT QWKEESRACI 720
SAPINGLLQV AKALIKSPTQ DQKLPTYLRD LSVSAGKEEQ DIRSSPGSLG AIISILDLLS 780
TVPTQVNSEM MRDILATINV ILDKSALNSW EKLLQQQSNQ SSQFLHSVER FSQALQLGDS 840
TPPFLAHPNV QMKSMVIKRG HPQIYQQQFI FKDSDLWGDV AIDECQLGNL QPDSSIVTVA 900
FPTLKAILAQ DVQRKTSSNS LVMTTTVSHN IVKPFRISMT FKNNHRSGGK PQCVFWNFSL 960
ANNTGGWDSS GCSVEDDGRD NRDRVFCKCN HLTSFSILMS PDSPDPGSLL KILLDIISYI 1020
GLGFSIVSLA ACLVVEAMVW KSVTKNRTSY MRHICIVNIA FCLLIADIWF IVAGAIHDGR 1080
YPLNETACVA ATFFIHFFYL SVFFWMLTLG LMLFYRLIFI LHDASKSTQK AIAFSLGYGC 1140
PLIISSITVG VTQPQEVYMR KNACWLNWED TRALLAFAIP ALIIVVVNVS ITVVVITKIL 1200
RPSIGDKPGK QEKSSLFQIS KSIGVLTPLL GLTWGFGLAT VIQGSNAVFH IIFTLLNAFQ 1260
GLFILLFGCL WDQKVQEALL HKFSLSRWSS QHSKSTSIGS STPVFSMSSP ISRRFNNLFG 1320
KTGTYNVSTP ETTSSSLENS SSAYSLLN 1348 
Gene Ontology
 GO:0016021; C:integral to membrane; IEA:UniProtKB-KW.
 GO:0005886; C:plasma membrane; IEA:UniProtKB-KW.
 GO:0004930; F:G-protein coupled receptor activity; IEA:InterPro.
 GO:0006112; P:energy reserve metabolic process; IMP:MGI.
 GO:0045444; P:fat cell differentiation; IMP:MGI.
 GO:0042593; P:glucose homeostasis; IMP:MGI.
 GO:0007218; P:neuropeptide signaling pathway; IEA:InterPro.
 GO:0019216; P:regulation of lipid metabolic process; IMP:MGI. 
Interpro
 IPR017981; GPCR_2-like.
 IPR008078; GPCR_2_Ig-hepta_rcpt.
 IPR000832; GPCR_2_secretin-like.
 IPR017983; GPCR_2_secretin-like_CS.
 IPR000203; GPS_dom.
 IPR007110; Ig-like_dom.
 IPR013783; Ig-like_fold.
 IPR013098; Ig_I-set.
 IPR003599; Ig_sub.
 IPR000082; SEA_dom. 
Pfam
 PF00002; 7tm_2
 PF01825; GPS
 PF07679; I-set
 PF01390; SEA 
SMART
 SM00303; GPS
 SM00409; IG 
PROSITE
 PS00650; G_PROTEIN_RECEP_F2_2
 PS50261; G_PROTEIN_RECEP_F2_4
 PS50221; GPS
 PS50835; IG_LIKE 
PRINTS
 PR00249; GPCRSECRETIN.
 PR01695; IGHEPTARCPTR.